In some autoimmune diseases, antibodies form that recognize other self-antibodies or DNA. A recent report in Nature implicates the Toll-like receptor 9 and innate immunity as a possible key to understanding the initiation of this process.
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Krieg, A. A role for Toll in autoimmunity. Nat Immunol 3, 423–424 (2002). https://doi.org/10.1038/ni0502-423
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DOI: https://doi.org/10.1038/ni0502-423
