close
Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Jun;23(3):547-64, ix-x.
doi: 10.1016/j.hoc.2009.03.009.

Melanoma and immunotherapy

Alexander M M Eggermont  1 , Dirk Schadendorf
Affiliations
Review

Melanoma and immunotherapy

Alexander M M Eggermont et al. Hematol Oncol Clin North Am. 2009 Jun.

Abstract

About 20% of all primary melanomas will spread. The likelihood of metastatic behavior correlates with prognostic factors such as tumor thickness, mitotic index, presence of ulceration, lymphocyte infiltration, age, gender, and anatomic site. Immunotherapies are developed for melanoma patients in stage IV who have distant metastases and in stage II to III patients in the adjuvant micrometastatic setting, where only a fraction of patients have widespread (microscopic) disease.

PubMed Disclaimer

MeSH terms