{"id":"https://openalex.org/W3203741947","doi":"https://doi.org/10.1016/j.softx.2021.100811","title":"pySuStaIn: A Python implementation of the Subtype and Stage Inference algorithm","display_name":"pySuStaIn: A Python implementation of the Subtype and Stage Inference algorithm","publication_year":2021,"publication_date":"2021-09-27","ids":{"openalex":"https://openalex.org/W3203741947","doi":"https://doi.org/10.1016/j.softx.2021.100811","mag":"3203741947","pmid":"https://pubmed.ncbi.nlm.nih.gov/34926780"},"language":"en","primary_location":{"id":"doi:10.1016/j.softx.2021.100811","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.softx.2021.100811","pdf_url":"http://www.softxjournal.com/article/S2352711021001096/pdf","source":{"id":"https://openalex.org/S2506067282","display_name":"SoftwareX","issn_l":"2352-7110","issn":["2352-7110"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SoftwareX","raw_type":"journal-article"},"type":"software-paper","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.softxjournal.com/article/S2352711021001096/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025836872","display_name":"Leon Aksman","orcid":"https://orcid.org/0000-0003-2342-0780"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB","US"],"is_corresponding":true,"raw_author_name":"Leon M. Aksman","raw_affiliation_strings":["Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California","Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, United States of America"],"raw_orcid":"https://orcid.org/0000-0003-2342-0780","affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, United States of America","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023797729","display_name":"P. A. Wijeratne","orcid":"https://orcid.org/0000-0002-4885-6241"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Peter A. Wijeratne","raw_affiliation_strings":["Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-4885-6241","affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075265609","display_name":"Neil P. Oxtoby","orcid":"https://orcid.org/0000-0003-0203-3909"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Neil P. Oxtoby","raw_affiliation_strings":["Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0003-0203-3909","affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048113582","display_name":"Arman Eshaghi","orcid":"https://orcid.org/0000-0002-6652-3512"},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]},{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Arman Eshaghi","raw_affiliation_strings":["Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London","Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253","https://openalex.org/I166337079"]},{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, United Kingdom","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253","https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086174310","display_name":"Cameron Shand","orcid":"https://orcid.org/0000-0002-1299-890X"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Cameron Shand","raw_affiliation_strings":["Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-1299-890X","affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069743881","display_name":"Andr\u00e9 Altmann","orcid":"https://orcid.org/0000-0002-9265-2393"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Andre Altmann","raw_affiliation_strings":["Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-9265-2393","affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Daniel C. Alexander","orcid":"https://orcid.org/0000-0002-7772-781X"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Daniel C. Alexander","raw_affiliation_strings":["Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-7772-781X","affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, Departments of Computer Science and Medical Physics, University College London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028056283","display_name":"Alexandra L. Young","orcid":"https://orcid.org/0000-0002-7772-781X"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Alexandra L. Young","raw_affiliation_strings":["Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London","Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King\u2019s College London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King\u2019s College London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5023797729","https://openalex.org/A5025836872","https://openalex.org/A5028056283","https://openalex.org/A5048113582","https://openalex.org/A5069743881","https://openalex.org/A5075265609","https://openalex.org/A5086174310"],"corresponding_institution_ids":["https://openalex.org/I1174212","https://openalex.org/I166337079","https://openalex.org/I183935753","https://openalex.org/I4210151618","https://openalex.org/I45129253"],"apc_list":{"value":500,"currency":"USD","value_usd":500},"apc_paid":{"value":500,"currency":"USD","value_usd":500},"fwci":null,"has_fulltext":true,"cited_by_count":82,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":null,"first_page":"100811","last_page":"100811"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12246","display_name":"Chronic Disease Management Strategies","score":0.9909999966621399,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.8962239027023315},{"id":"https://openalex.org/keywords/subtyping","display_name":"Subtyping","score":0.8655216693878174},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7093824148178101},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.6886367201805115},{"id":"https://openalex.org/keywords/translation","display_name":"Translation (biology)","score":0.41532444953918457},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.34874606132507324},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.331091046333313},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3235466480255127},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.0924685001373291}],"concepts":[{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.8962239027023315},{"id":"https://openalex.org/C83852419","wikidata":"https://www.wikidata.org/wiki/Q2713292","display_name":"Subtyping","level":2,"score":0.8655216693878174},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7093824148178101},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.6886367201805115},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.41532444953918457},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.34874606132507324},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.331091046333313},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3235466480255127},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0924685001373291},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.softx.2021.100811","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.softx.2021.100811","pdf_url":"http://www.softxjournal.com/article/S2352711021001096/pdf","source":{"id":"https://openalex.org/S2506067282","display_name":"SoftwareX","issn_l":"2352-7110","issn":["2352-7110"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SoftwareX","raw_type":"journal-article"},{"id":"pmid:34926780","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34926780","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SoftwareX","raw_type":null},{"id":"pmh:oai:doaj.org/article:60d8182a3cf14e42a3e007c21dcc0379","is_oa":true,"landing_page_url":"https://doaj.org/article/60d8182a3cf14e42a3e007c21dcc0379","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"SoftwareX, Vol 16, Iss , Pp 100811- (2021)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8682799","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8682799","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"SoftwareX","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.softx.2021.100811","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.softx.2021.100811","pdf_url":"http://www.softxjournal.com/article/S2352711021001096/pdf","source":{"id":"https://openalex.org/S2506067282","display_name":"SoftwareX","issn_l":"2352-7110","issn":["2352-7110"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SoftwareX","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1096768342","display_name":"Computational models for clinical trial design in Huntington's disease","funder_award_id":"MR/T027770/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G1735096943","display_name":null,"funder_award_id":"MR/T027800/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2373214691","display_name":null,"funder_award_id":"PA-1412-0242","funder_id":"https://openalex.org/F4320320084","funder_display_name":"Multiple Sclerosis Society"},{"id":"https://openalex.org/G2413268702","display_name":null,"funder_award_id":"P30AG066530","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G2810234172","display_name":null,"funder_award_id":"P41EB015922","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3264764772","display_name":null,"funder_award_id":"P30 AG066530","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G333842167","display_name":"I-AIM: Individualised Artificial Intelligence for Medicine","funder_award_id":"MR/S03546X/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4284698765","display_name":"Data-driven models for Progression Of Neurological Disease","funder_award_id":"666992","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4669776581","display_name":null,"funder_award_id":"MR/S03546X/1","funder_id":"https://openalex.org/F4320314731","funder_display_name":"UK Research and Innovation"},{"id":"https://openalex.org/G4939262165","display_name":null,"funder_award_id":"PA-1412-0242","funder_id":"https://openalex.org/F4320317151","funder_display_name":"International Progressive MS Alliance"},{"id":"https://openalex.org/G5619513383","display_name":null,"funder_award_id":"MR/S03546X/1","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G7206553482","display_name":"MICA: Medical Bioinformatics: Data-Driven Discovery for Personalised Medicine","funder_award_id":"MR/L016311/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7329585684","display_name":null,"funder_award_id":"MR/T027770/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7862106776","display_name":null,"funder_award_id":"P41 EB015922","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G8268424837","display_name":null,"funder_award_id":"MR/L016311/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G8471428477","display_name":null,"funder_award_id":"P30AG066530","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8645188002","display_name":null,"funder_award_id":"666992","funder_id":"https://openalex.org/F4320314745","funder_display_name":"FP7 Coherent Development of Research Policies"}],"funders":[{"id":"https://openalex.org/F4320314731","display_name":"UK Research and Innovation","ror":"https://ror.org/001aqnf71"},{"id":"https://openalex.org/F4320314745","display_name":"FP7 Coherent Development of Research Policies","ror":null},{"id":"https://openalex.org/F4320317151","display_name":"International Progressive MS Alliance","ror":null},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320084","display_name":"Multiple Sclerosis Society","ror":"https://ror.org/043fwdk81"},{"id":"https://openalex.org/F4320320286","display_name":"University College London","ror":"https://ror.org/02jx3x895"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320335254","display_name":"Horizon 2020","ror":null},{"id":"https://openalex.org/F4320335827","display_name":"UCLH Biomedical Research Centre","ror":"https://ror.org/03r9qc142"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3203741947.pdf","grobid_xml":"https://content.openalex.org/works/W3203741947.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1968698114","https://openalex.org/W2075444764","https://openalex.org/W2086080135","https://openalex.org/W2102932082","https://openalex.org/W2110759468","https://openalex.org/W2136195493","https://openalex.org/W2147062889","https://openalex.org/W2168818001","https://openalex.org/W2577478840","https://openalex.org/W2782660935","https://openalex.org/W2982614698","https://openalex.org/W3006513902","https://openalex.org/W3031318751","https://openalex.org/W3105808417","https://openalex.org/W3112243371","https://openalex.org/W3148523720","https://openalex.org/W3157186248","https://openalex.org/W3198249985","https://openalex.org/W6676412653","https://openalex.org/W6732294759","https://openalex.org/W6793703961","https://openalex.org/W6793914820"],"related_works":["https://openalex.org/W2396009657","https://openalex.org/W2799110842","https://openalex.org/W3032826521","https://openalex.org/W2391332606","https://openalex.org/W1462775415","https://openalex.org/W1987896487","https://openalex.org/W4229853287","https://openalex.org/W1535483699","https://openalex.org/W2207495067","https://openalex.org/W1906486629"],"abstract_inverted_index":{"Progressive":[0],"disorders":[1,10],"are":[2,39,92],"highly":[3],"heterogeneous.":[4],"Symptom-based":[5],"clinical":[6,44],"classification":[7],"of":[8,21,32,58,70,90,99],"these":[9],"may":[11],"not":[12],"reflect":[13],"the":[14,24,28,51,59,68],"underlying":[15],"pathobiology.":[16],"Data-driven":[17],"subtyping":[18],"and":[19,45,61,80,97,110],"staging":[20],"patients":[22],"has":[23],"potential":[25],"to":[26,93,112],"disentangle":[27],"complex":[29],"spatiotemporal":[30],"patterns":[31,78],"disease":[33,76],"progression.":[34],"Tools":[35],"that":[36,106],"enable":[37,94],"this":[38],"in":[40],"high":[41],"demand":[42],"from":[43,84],"treatment-development":[46],"communities.":[47],"Here":[48],"we":[49],"describe":[50],"pySuStaIn":[52,91],"software":[53],"package,":[54],"a":[55,117],"Python-based":[56],"implementation":[57],"Subtype":[60],"Stage":[62],"Inference":[63],"(SuStaIn)":[64],"algorithm.":[65],"SuStaIn":[66,100],"unravels":[67],"complexity":[69],"heterogeneous":[71],"diseases":[72],"by":[73],"inferring":[74],"multiple":[75],"progression":[77],"(subtypes)":[79],"individual":[81],"severity":[82],"(stages)":[83],"cross-sectional":[85],"data.":[86],"The":[87],"primary":[88],"aims":[89],"widespread":[95],"application":[96],"translation":[98],"via":[101],"an":[102],"accessible":[103],"Python":[104],"package":[105],"supports":[107],"simple":[108],"extension":[109],"generalization":[111],"novel":[113],"modeling":[114],"situations":[115],"within":[116],"single,":[118],"consistent":[119],"architecture.":[120]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":26},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":4}],"updated_date":"2026-07-16T13:24:37.021932","created_date":"2025-10-10T00:00:00"}