{"id":"https://openalex.org/W2973839948","doi":"https://doi.org/10.1109/coase.2019.8842860","title":"Mosquito Pick-and-Place: Automating a Key Step in PfSPZ-based Malaria Vaccine Production","display_name":"Mosquito Pick-and-Place: Automating a Key Step in PfSPZ-based Malaria Vaccine Production","publication_year":2019,"publication_date":"2019-08-01","ids":{"openalex":"https://openalex.org/W2973839948","doi":"https://doi.org/10.1109/coase.2019.8842860","mag":"2973839948"},"language":"en","primary_location":{"id":"doi:10.1109/coase.2019.8842860","is_oa":false,"landing_page_url":"https://doi.org/10.1109/coase.2019.8842860","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 15th International Conference on Automation Science and Engineering (CASE)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042944948","display_name":"Henry Phalen","orcid":"https://orcid.org/0000-0002-6854-6582"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Henry Phalen","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029253617","display_name":"Prasad Vagdargi","orcid":"https://orcid.org/0000-0002-2740-6604"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prasad Vagdargi","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049914910","display_name":"Michael Pozin","orcid":"https://orcid.org/0000-0002-9069-7440"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Pozin","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087910015","display_name":"Sumana Chakravarty","orcid":"https://orcid.org/0000-0002-0426-6418"},"institutions":[{"id":"https://openalex.org/I4210089633","display_name":"Sanaria","ror":"https://ror.org/0092qhe76","country_code":"US","type":"company","lineage":["https://openalex.org/I4210089633"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sumana Chakravarty","raw_affiliation_strings":["Sanaria, Inc. Rockville, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanaria, Inc. Rockville, MD, USA","institution_ids":["https://openalex.org/I4210089633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012775344","display_name":"Gregory S. Chirikjian","orcid":"https://orcid.org/0000-0003-0542-9028"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory S. Chirikjian","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063913520","display_name":"Iulian Iordachita","orcid":"https://orcid.org/0000-0002-2510-9008"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iulian Iordachita","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004170925","display_name":"Russell H. Taylor","orcid":"https://orcid.org/0000-0001-6272-1100"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell H. Taylor","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR) at the, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"67","issue":null,"first_page":"12","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11684","display_name":"Vibrio bacteria research studies","score":0.9750000238418579,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.6211121082305908},{"id":"https://openalex.org/keywords/automation","display_name":"Automation","score":0.5864241123199463},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5349295139312744},{"id":"https://openalex.org/keywords/malaria-vaccine","display_name":"Malaria vaccine","score":0.45086437463760376},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.450244665145874},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4291130304336548},{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.370799720287323},{"id":"https://openalex.org/keywords/simulation","display_name":"Simulation","score":0.3677466809749603},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3309480547904968},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.2658650577068329},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.19451135396957397},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.14129853248596191}],"concepts":[{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.6211121082305908},{"id":"https://openalex.org/C115901376","wikidata":"https://www.wikidata.org/wiki/Q184199","display_name":"Automation","level":2,"score":0.5864241123199463},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5349295139312744},{"id":"https://openalex.org/C2781034427","wikidata":"https://www.wikidata.org/wiki/Q6741353","display_name":"Malaria vaccine","level":4,"score":0.45086437463760376},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.450244665145874},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4291130304336548},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.370799720287323},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.3677466809749603},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3309480547904968},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2658650577068329},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19451135396957397},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.14129853248596191},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/coase.2019.8842860","is_oa":false,"landing_page_url":"https://doi.org/10.1109/coase.2019.8842860","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 15th International Conference on Automation Science and Engineering (CASE)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8600000143051147,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1979427692","https://openalex.org/W2122753628","https://openalex.org/W2133059825","https://openalex.org/W2346928357","https://openalex.org/W2536329697","https://openalex.org/W2571810950","https://openalex.org/W2587907012","https://openalex.org/W2588256621","https://openalex.org/W2591439676","https://openalex.org/W2779022925","https://openalex.org/W2893696675","https://openalex.org/W2922763470","https://openalex.org/W2974096238","https://openalex.org/W2974497600","https://openalex.org/W6682173217","https://openalex.org/W6760888924"],"related_works":["https://openalex.org/W2131277865","https://openalex.org/W2088582527","https://openalex.org/W4401623603","https://openalex.org/W2954706416","https://openalex.org/W2405847924","https://openalex.org/W2942187201","https://openalex.org/W2178803407","https://openalex.org/W3217358840","https://openalex.org/W4400408704","https://openalex.org/W4319459473"],"abstract_inverted_index":{"The":[0],"treatment":[1],"of":[2,17,38,51,74,86,99,116,123,141,149,178,186,234],"malaria":[3],"is":[4,105,162,221,250],"a":[5,18,30,75,89,93,100,108,113,124,133,139,194,199,222,253],"global":[6],"health":[7],"challenge":[8],"that":[9,214],"stands":[10],"to":[11,28,58,112,138,145,154,170,242],"benefit":[12],"from":[13,88,132,167],"the":[14,21,35,39,48,72,82,121,147,150,155,173,187,204,210,215,235],"widespread":[15],"introduction":[16],"vaccine":[19,33,68],"for":[20,66,172,225,240],"disease.":[22],"A":[23],"method":[24],"has":[25],"been":[26],"developed":[27],"create":[29],"live":[31],"organism":[32],"using":[34,107],"sporozoites":[36],"(SPZ)":[37],"parasite":[40],"Plasmodium":[41],"falciparum":[42],"(Pf),":[43],"which":[44],"are":[45,62,129],"concentrated":[46],"in":[47,78,202],"salivary":[49,156],"glands":[50],"infected":[52],"mosquitoes.":[53],"Current":[54],"manual":[55],"dissection":[56,94,143,257],"methods":[57],"obtain":[59],"these":[60,160],"PfSPZ":[61],"not":[63],"optimally":[64],"efficient":[65],"large-scale":[67],"production.":[69],"We":[70],"demonstrate":[71,193],"automation":[73],"key":[76],"step":[77],"this":[79,183,226,246],"production":[80],"process,":[81],"picking":[83],"and":[84,136,176,198,228],"placing":[85,203],"mosquitoes":[87],"staging":[90],"apparatus":[91],"into":[92,159,252],"assembly.":[95],"This":[96,220],"unit":[97],"test":[98,185],"robotic":[101,247],"mosquito":[102,205,256],"pick-and-place":[103,230,248],"system":[104,188,249,258],"performed":[106],"custom-designed":[109],"micro-gripper":[110],"attached":[111],"four":[114],"degree":[115],"freedom":[117],"(4-DOF)":[118],"robot":[119],"under":[120,259],"guidance":[122],"computer":[125,168],"vision":[126,169],"system.":[127],"Mosquitoes":[128],"autonomously":[130],"grasped":[131,180],"mesh":[134],"platform":[135],"pulled":[137],"pair":[140],"notched":[142],"blades":[144,161],"remove":[146],"head":[148,216],"mosquito,":[151],"allowing":[152],"access":[153],"glands.":[157],"Placement":[158],"adapted":[163],"based":[164],"on":[165,189],"output":[166],"accommodate":[171],"unique":[174],"anatomy":[175],"orientation":[177],"each":[179],"mosquito.":[181],"In":[182],"pilot":[184],"50":[190],"mosquitoes,":[191],"we":[192],"100%":[195],"grasping":[196],"accuracy":[197,201],"90%":[200],"with":[206],"its":[207],"neck":[208],"within":[209],"blade":[211],"notches":[212],"such":[213],"can":[217],"be":[218,243],"removed.":[219],"promising":[223],"result":[224],"difficult":[227],"non-standard":[229],"task.":[231],"An":[232],"analysis":[233],"failure":[236],"cases":[237],"provides":[238],"insights":[239],"improvements":[241],"implemented":[244],"as":[245],"integrated":[251],"larger":[254],"automated":[255],"development.":[260]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}