{"id":"https://openalex.org/W4285805236","doi":"https://doi.org/10.1145/3520304.3528802","title":"BOBEA","display_name":"BOBEA","publication_year":2022,"publication_date":"2022-07-09","ids":{"openalex":"https://openalex.org/W4285805236","doi":"https://doi.org/10.1145/3520304.3528802"},"language":"en","primary_location":{"id":"doi:10.1145/3520304.3528802","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3520304.3528802","pdf_url":null,"source":{"id":"https://openalex.org/S4363608771","display_name":"Proceedings of the Genetic and Evolutionary Computation Conference Companion","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Genetic and Evolutionary Computation Conference Companion","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056544529","display_name":"Ons Ma\u00e2touk","orcid":"https://orcid.org/0000-0002-1828-3657"},"institutions":[{"id":"https://openalex.org/I108714496","display_name":"Tunis University","ror":"https://ror.org/02q1spa57","country_code":"TN","type":"education","lineage":["https://openalex.org/I108714496"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Ons Maatouk","raw_affiliation_strings":["University of Tunis, Tunis, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Tunis, Tunis, Tunisia","institution_ids":["https://openalex.org/I108714496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027747484","display_name":"Emna Ayari","orcid":"https://orcid.org/0000-0002-8660-2437"},"institutions":[{"id":"https://openalex.org/I108714496","display_name":"Tunis University","ror":"https://ror.org/02q1spa57","country_code":"TN","type":"education","lineage":["https://openalex.org/I108714496"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Emna Ayari","raw_affiliation_strings":["University of Tunis, Tunis, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Tunis, Tunis, Tunisia","institution_ids":["https://openalex.org/I108714496"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024391016","display_name":"Hend Bouziri","orcid":"https://orcid.org/0000-0003-3773-7068"},"institutions":[{"id":"https://openalex.org/I108714496","display_name":"Tunis University","ror":"https://ror.org/02q1spa57","country_code":"TN","type":"education","lineage":["https://openalex.org/I108714496"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Hend Bouziri","raw_affiliation_strings":["University of Tunis, Tunis, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Tunis, Tunis, Tunisia","institution_ids":["https://openalex.org/I108714496"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013874328","display_name":"Wassim Ayadi","orcid":"https://orcid.org/0000-0002-4017-6057"},"institutions":[{"id":"https://openalex.org/I63596082","display_name":"Tunis El Manar University","ror":"https://ror.org/029cgt552","country_code":"TN","type":"education","lineage":["https://openalex.org/I63596082"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Wassim Ayadi","raw_affiliation_strings":["University of Tunis El Manar, Tunis, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Tunis El Manar, Tunis, Tunisia","institution_ids":["https://openalex.org/I63596082"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"344","last_page":"347"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9829999804496765,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/snp","display_name":"SNP","score":0.6258341073989868},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5962474346160889},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5674748420715332},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.5618539452552795},{"id":"https://openalex.org/keywords/biclustering","display_name":"Biclustering","score":0.5589578747749329},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"Genome-wide association study","score":0.4989485740661621},{"id":"https://openalex.org/keywords/genetic-association","display_name":"Genetic association","score":0.4602429270744324},{"id":"https://openalex.org/keywords/complex-disease","display_name":"Complex disease","score":0.4511588513851166},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.43034815788269043},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3542971611022949},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.329984575510025},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.32689037919044495},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2756109833717346},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.22680890560150146},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.20861992239952087},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.12344950437545776},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.08343157172203064}],"concepts":[{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.6258341073989868},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5962474346160889},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5674748420715332},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.5618539452552795},{"id":"https://openalex.org/C144817290","wikidata":"https://www.wikidata.org/wiki/Q2976575","display_name":"Biclustering","level":5,"score":0.5589578747749329},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.4989485740661621},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.4602429270744324},{"id":"https://openalex.org/C3018605307","wikidata":"https://www.wikidata.org/wiki/Q200779","display_name":"Complex disease","level":3,"score":0.4511588513851166},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.43034815788269043},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3542971611022949},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.329984575510025},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32689037919044495},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2756109833717346},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.22680890560150146},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20861992239952087},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.12344950437545776},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08343157172203064},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C33704608","wikidata":"https://www.wikidata.org/wiki/Q5014717","display_name":"CURE data clustering algorithm","level":4,"score":0.0},{"id":"https://openalex.org/C94641424","wikidata":"https://www.wikidata.org/wiki/Q5172845","display_name":"Correlation clustering","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3520304.3528802","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3520304.3528802","pdf_url":null,"source":{"id":"https://openalex.org/S4363608771","display_name":"Proceedings of the Genetic and Evolutionary Computation Conference Companion","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Genetic and Evolutionary Computation Conference Companion","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1493217831","https://openalex.org/W1891744697","https://openalex.org/W2021993511","https://openalex.org/W2041969839","https://openalex.org/W2064539914","https://openalex.org/W2104093114","https://openalex.org/W2105883975","https://openalex.org/W2128380033","https://openalex.org/W2137596615","https://openalex.org/W2143065952","https://openalex.org/W2143274936","https://openalex.org/W2167280276","https://openalex.org/W2725433940","https://openalex.org/W2756677578","https://openalex.org/W2884930948","https://openalex.org/W3119505072","https://openalex.org/W3131242005","https://openalex.org/W6629329278"],"related_works":["https://openalex.org/W1971424770","https://openalex.org/W2111842731","https://openalex.org/W2066467839","https://openalex.org/W2594299395","https://openalex.org/W2765794416","https://openalex.org/W2170506381","https://openalex.org/W1992310781","https://openalex.org/W2887190046","https://openalex.org/W4247775625","https://openalex.org/W2151668213"],"abstract_inverted_index":{"The":[0],"behavior":[1],"of":[2,27,38,75,81,139,155,171],"many":[3,28,64],"diseases":[4,66],"is":[5,84,112,125,162],"still":[6],"not":[7],"well":[8],"understood":[9],"by":[10],"researchers.":[11],"Genome-Wide":[12,157],"Association":[13],"(GWA)":[14],"analyzes":[15,32],"have":[16,67],"recently":[17],"become":[18],"a":[19,109,149],"popular":[20],"approach":[21,151],"to":[22,35,70,99,114,167],"discovering":[23],"the":[24,36,51,58,79,97,137,153,156,169,172],"genetic":[25,39,54],"causes":[26],"complex":[29,65],"diseases.":[30],"These":[31,47],"could":[33],"lead":[34],"discovery":[37],"factors":[40],"potentially":[41],"involved":[42,103],"in":[43,96,104,136],"certain":[44],"disease":[45,122],"susceptibility.":[46,123],"studies":[48],"typically":[49],"use":[50],"most":[52],"common":[53],"variation":[55,102],"between":[56,118],"individuals,":[57],"Single":[59],"Nucleotide":[60],"Polymorphism":[61],"(SNP).":[62],"Indeed,":[63],"been":[68],"revealed":[69],"be":[71],"associated":[72],"with":[73],"combinations":[74],"SNP":[76,119],"interactions.":[77],"However,":[78],"identification":[80],"such":[82,101],"interactions":[83],"considered":[85],"difficult.":[86],"Therefore,":[87],"various":[88],"unsupervised":[89,127],"data":[90,166],"mining":[91],"methods":[92],"are":[93,177],"often":[94],"developed":[95],"literature":[98],"identify":[100],"disease.":[105],"In":[106],"this":[107],"work,":[108],"biclustering":[110,154],"method":[111],"adopted":[113],"detect":[115],"possible":[116],"associations":[117],"markers":[120],"and":[121],"It":[124],"an":[126,132,144],"classification":[128],"technique,":[129],"which":[130],"plays":[131],"increasingly":[133],"important":[134],"role":[135],"study":[138,161],"modern":[140],"biology.":[141],"We":[142],"propose":[143],"evolutionary":[145],"algorithm":[146],"based":[147],"on":[148,164],"bi-objective":[150],"for":[152],"Association.":[158],"An":[159],"experimental":[160],"achieved":[163],"synthetic":[165],"evaluate":[168],"performance":[170],"proposed":[173],"algorithm.":[174],"Promising":[175],"results":[176],"obtained.":[178]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2022-07-19T00:00:00"}