{"id":"https://openalex.org/W4390437083","doi":"https://doi.org/10.3390/data9010008","title":"DNA Methylome and Transcriptome Maps of Primary Colorectal Cancer and Matched Liver Metastasis","display_name":"DNA Methylome and Transcriptome Maps of Primary Colorectal Cancer and Matched Liver Metastasis","publication_year":2023,"publication_date":"2023-12-29","ids":{"openalex":"https://openalex.org/W4390437083","doi":"https://doi.org/10.3390/data9010008"},"language":"en","primary_location":{"id":"doi:10.3390/data9010008","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/data9010008","pdf_url":"https://www.mdpi.com/2306-5729/9/1/8/pdf?version=1704772306","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2306-5729/9/1/8/pdf?version=1704772306","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004136574","display_name":"Priyadarshana Ajithkumar","orcid":null},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Priyadarshana Ajithkumar","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045884039","display_name":"Gr\u00e9gory Gimenez","orcid":null},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Gregory Gimenez","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064788440","display_name":"Peter A. Stockwell","orcid":"https://orcid.org/0000-0002-2145-3493"},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Peter A. Stockwell","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":"https://orcid.org/0000-0002-2145-3493","affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015821230","display_name":"Suzan Almomani","orcid":null},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Suzan Almomani","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030494809","display_name":"Sarah A. Bowden","orcid":"https://orcid.org/0000-0003-4115-7955"},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Sarah A. Bowden","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048787520","display_name":"Anna L. Leichter","orcid":"https://orcid.org/0000-0002-4914-4393"},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Anna L. Leichter","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":"https://orcid.org/0000-0002-4914-4393","affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082237249","display_name":"Antonio Ahn","orcid":"https://orcid.org/0000-0003-4053-5467"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I2800555584","display_name":"Peter MacCallum Cancer Centre","ror":"https://ror.org/02a8bt934","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800555584"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Antonio Ahn","raw_affiliation_strings":["Peter MacCallum Cancer Centre, Melbourne, VIC 3052, Australia","The Sir Peter MacCallum Department of Oncology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC 3052, Australia","of , of , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peter MacCallum Cancer Centre, Melbourne, VIC 3052, Australia","institution_ids":["https://openalex.org/I2800555584"]},{"raw_affiliation_string":"The Sir Peter MacCallum Department of Oncology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC 3052, Australia","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I2800555584"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065893122","display_name":"Sharon Pattison","orcid":"https://orcid.org/0000-0003-2188-3423"},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Sharon Pattison","raw_affiliation_strings":["Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":"https://orcid.org/0000-0003-2188-3423","affiliations":[{"raw_affiliation_string":"Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033539188","display_name":"Sebastian Schmeier","orcid":"https://orcid.org/0000-0002-3947-8226"},"institutions":[{"id":"https://openalex.org/I4210130816","display_name":"Evotec (Germany)","ror":"https://ror.org/03d3v3e93","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210130816"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sebastian Schmeier","raw_affiliation_strings":["Evotec SE, 22419 Hamburg, Germany","of , of , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Evotec SE, 22419 Hamburg, Germany","institution_ids":["https://openalex.org/I4210130816"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064756982","display_name":"Frank Frizelle","orcid":"https://orcid.org/0000-0002-0739-4802"},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Frank A. Frizelle","raw_affiliation_strings":["Department of Surgery, University of Otago, Christchurch 8011, New Zealand","of , of , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, University of Otago, Christchurch 8011, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090852800","display_name":"Michael R. Eccles","orcid":"https://orcid.org/0000-0002-6824-8761"},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Michael R. Eccles","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":"https://orcid.org/0000-0002-6824-8761","affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087129397","display_name":"Rachel Purcell","orcid":"https://orcid.org/0000-0002-2684-4530"},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Rachel V. Purcell","raw_affiliation_strings":["Department of Surgery, University of Otago, Christchurch 8011, New Zealand","of , of , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, University of Otago, Christchurch 8011, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062599999","display_name":"Euan J. Rodger","orcid":"https://orcid.org/0000-0002-9615-5896"},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Euan J. Rodger","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","of , of , ,"],"raw_orcid":"https://orcid.org/0000-0002-9615-5896","affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042462309","display_name":"Aniruddha Chatterjee","orcid":"https://orcid.org/0000-0001-7276-2248"},"institutions":[{"id":"https://openalex.org/I5847235","display_name":"University of Petroleum and Energy Studies","ror":"https://ror.org/04q2jes40","country_code":"IN","type":"education","lineage":["https://openalex.org/I5847235"]},{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["IN","NZ"],"is_corresponding":true,"raw_author_name":"Aniruddha Chatterjee","raw_affiliation_strings":["Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","UPES University, Dehradun 248007, India","of , of , ,"],"raw_orcid":"https://orcid.org/0000-0001-7276-2248","affiliations":[{"raw_affiliation_string":"Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"UPES University, Dehradun 248007, India","institution_ids":["https://openalex.org/I5847235"]},{"raw_affiliation_string":"of , of , ,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5042462309","https://openalex.org/A5062599999","https://openalex.org/A5087129397"],"corresponding_institution_ids":["https://openalex.org/I5847235","https://openalex.org/I80281795"],"apc_list":{"value":1600,"currency":"CHF","value_usd":1732},"apc_paid":{"value":1600,"currency":"CHF","value_usd":1732},"fwci":0.1345,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.59212986,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"9","issue":"1","first_page":"8","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.7333147525787354},{"id":"https://openalex.org/keywords/epigenetics","display_name":"Epigenetics","score":0.6933515071868896},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6535673141479492},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.6183493137359619},{"id":"https://openalex.org/keywords/metastasis","display_name":"Metastasis","score":0.5961431860923767},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4513798952102661},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"Colorectal cancer","score":0.43320411443710327},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.43227121233940125},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4304201900959015},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.4126688539981842},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3819248676300049},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.34222668409347534},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.329906165599823},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.32329100370407104},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.29305267333984375}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7333147525787354},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6933515071868896},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6535673141479492},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.6183493137359619},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5961431860923767},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4513798952102661},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.43320411443710327},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.43227121233940125},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4304201900959015},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.4126688539981842},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3819248676300049},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.34222668409347534},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.329906165599823},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.32329100370407104},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.29305267333984375}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/data9010008","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/data9010008","pdf_url":"https://www.mdpi.com/2306-5729/9/1/8/pdf?version=1704772306","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},{"id":"pmh:oai:RePEc:gam:jdataj:v:9:y:2023:i:1:p:8-:d:1310308","is_oa":false,"landing_page_url":"https://www.mdpi.com/2306-5729/9/1/8/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:f34097822278464bb35e8c3ac67bf4d0","is_oa":true,"landing_page_url":"https://doaj.org/article/f34097822278464bb35e8c3ac67bf4d0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Data, Vol 9, Iss 1, p 8 (2023)","raw_type":"article"},{"id":"pmh:oai:mdpi.com:/2306-5729/9/1/8/","is_oa":true,"landing_page_url":"https://doi.org/10.3390/data9010008","pdf_url":null,"source":{"id":"https://openalex.org/S4306400947","display_name":"MDPI (MDPI AG)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210097602","host_organization_name":"Multidisciplinary Digital Publishing Institute (Switzerland)","host_organization_lineage":["https://openalex.org/I4210097602"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Data","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/data9010008","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/data9010008","pdf_url":"https://www.mdpi.com/2306-5729/9/1/8/pdf?version=1704772306","source":{"id":"https://openalex.org/S4210226510","display_name":"Data","issn_l":"2306-5729","issn":["2306-5729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Data","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310371","display_name":"University of Otago","ror":"https://ror.org/01jmxt844"},{"id":"https://openalex.org/F4320327639","display_name":"Centre Scientifique et Technique du B\u00e2timent","ror":"https://ror.org/02fsd1928"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390437083.pdf","grobid_xml":"https://content.openalex.org/works/W4390437083.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1967269029","https://openalex.org/W2002876239","https://openalex.org/W2005607945","https://openalex.org/W2019390139","https://openalex.org/W2019420944","https://openalex.org/W2049015838","https://openalex.org/W2074045502","https://openalex.org/W2085582536","https://openalex.org/W2097681338","https://openalex.org/W2099002142","https://openalex.org/W2102278945","https://openalex.org/W2104082768","https://openalex.org/W2131232216","https://openalex.org/W2131374955","https://openalex.org/W2131829779","https://openalex.org/W2138207763","https://openalex.org/W2146862337","https://openalex.org/W2158774461","https://openalex.org/W2301702458","https://openalex.org/W2432815617","https://openalex.org/W2486011972","https://openalex.org/W2529145719","https://openalex.org/W2614855875","https://openalex.org/W2904364231","https://openalex.org/W2907808933","https://openalex.org/W2916883272","https://openalex.org/W2919021755","https://openalex.org/W3006834559","https://openalex.org/W3035055581","https://openalex.org/W3168769735","https://openalex.org/W3192596566","https://openalex.org/W3199793491","https://openalex.org/W4200200165","https://openalex.org/W4200456285","https://openalex.org/W4210700245","https://openalex.org/W4214774902","https://openalex.org/W4224880107","https://openalex.org/W4281909401","https://openalex.org/W4289836879","https://openalex.org/W4295096627","https://openalex.org/W4307401860","https://openalex.org/W4313897281","https://openalex.org/W4378594183","https://openalex.org/W4385342375","https://openalex.org/W4388581469","https://openalex.org/W4388869662","https://openalex.org/W6803304623"],"related_works":["https://openalex.org/W2214376880","https://openalex.org/W3212149434","https://openalex.org/W2073893804","https://openalex.org/W2291484187","https://openalex.org/W2898448758","https://openalex.org/W2902329290","https://openalex.org/W2802827720","https://openalex.org/W2139872319","https://openalex.org/W2052355316","https://openalex.org/W2046964473"],"abstract_inverted_index":{"Sequencing-based":[0],"genome-wide":[1],"DNA":[2,26,60],"methylation,":[3],"gene":[4],"expression":[5,45,63],"studies":[6],"and":[7,16,28,34,44,55,62,75,97,112,140],"associated":[8],"data":[9,114,122],"on":[10],"paired":[11,118],"colorectal":[12],"cancer":[13,84,147],"(CRC)":[14],"primary":[15,32],"liver":[17,35],"metastasis":[18,36,139],"are":[19],"very":[20],"limited.":[21],"We":[22,104],"have":[23],"profiled":[24],"the":[25,39,82,91,106,110,117,141],"methylome":[27],"transcriptome":[29],"of":[30,69,108,137,143],"matched":[31,83],"CRC":[33],"samples":[37,111],"from":[38,81,116,124],"same":[40],"patients.":[41],"Genome-scale":[42],"methylation":[43,61],"levels":[46],"were":[47],"examined":[48],"using":[49],"Reduced":[50],"Representation":[51],"Bisulfite":[52],"Sequencing":[53],"(RRBS)":[54],"RNA-Seq,":[56],"respectively.":[57],"To":[58],"investigate":[59],"patterns,":[64],"we":[65,87],"generated":[66],"a":[67,130],"total":[68],"1.01":[70],"\u00d7":[71,77],"109":[72],"RRBS":[73],"reads":[74,80],"4.38":[76],"108":[78],"RNA-Seq":[79],"tissues.":[85],"Here,":[86],"describe":[88],"in":[89,146],"detail":[90],"sample":[92],"features,":[93],"experimental":[94],"design,":[95],"methods":[96],"bioinformatic":[98],"pipeline":[99],"for":[100,133],"these":[101],"epigenetic":[102,144],"data.":[103],"demonstrate":[105],"quality":[107],"both":[109],"sequence":[113],"obtained":[115,123],"samples.":[119],"The":[120],"sequencing":[121],"this":[125],"study":[126],"will":[127],"serve":[128],"as":[129],"valuable":[131],"resource":[132],"studying":[134],"underlying":[135],"mechanisms":[136],"distant":[138],"utility":[142],"profiles":[145],"metastasis.":[148]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}