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Multimodal Fusion for Melanoma Classification Using Dermoscopic Images and Clinical Metadata

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Medical Image Computing in Resource Constrained Settings (MIRASOL 2025)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 16398))

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Abstract

Melanoma diagnosis, a particularly aggressive form of skin cancer, remains challenging due to the variability of lesions. To improve classification accuracy, we propose a novel multimodal approach combining dermoscopic images and clinical metadata (sex, age, anatomical location). Our architecture relies on different visual backbones (Vision Transformer, ResNet, EfficientNet) for image feature extraction, coupled with a multilayer perceptron (MLP) dedicated to metadata encoding. The two branches are fused to produce a joint prediction. Results show that the MultimodalViTModel achieves the best overall performance (F1-score of 0.8897, accuracy of 0.9955), closely followed by the MultimodalResNet. The MultimodalEfficientNet model exhibits greater variability on minority classes. In comparison, a baseline model relying solely on images performs worse, confirming the added value of integrating clinical metadata. Finally, the complexity analysis reveals that ResNet represents an excellent trade-off between efficiency and accuracy, making it suitable for constrained clinical settings. Our code will be publicly available at: https://github.com/Aby1diallo/Skin_lesion.

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Diallo, A., Allaya, M.M., Samb, D., Elbatel, M., Lo, S., Bousso, M. (2026). Multimodal Fusion for Melanoma Classification Using Dermoscopic Images and Clinical Metadata. In: Anazodo, U., Zhang, D., Raymond, C., Kurt, M., Lekadir, K., Crimi, A. (eds) Medical Image Computing in Resource Constrained Settings. MIRASOL 2025. Lecture Notes in Computer Science, vol 16398. Springer, Cham. https://doi.org/10.1007/978-3-032-13654-1_3

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