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Review
. 2008 Jun 7;14(21):3301-5.
doi: 10.3748/wjg.14.3301.

Clinical features and management of autoimmune hepatitis

Edward-L Krawitt  1
Affiliations
Review

Clinical features and management of autoimmune hepatitis

Edward-L Krawitt. World J Gastroenterol. .

Abstract

Autoimmune hepatitis (AIH) is a chronic hepatitis of unknown etiology which can progress to cirrhosis. Its clinical manifestations are highly variable and sometimes follow a fluctuating course. Diagnosis is based on characteristic histologic, clinical, biochemical and serological findings. Anti-inflammatory/immunosuppressive treatment frequently induces remission but long-term maintenance therapy is often required. Liver transplantation is generally successful in patients with decompensated cirrhosis unresponsive to or intolerant of medical therapy.

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