{"id":"https://openalex.org/W1974632212","doi":"https://doi.org/10.1109/embc.2012.6346432","title":"Unsupervised tumour segmentation in PET based on local and global intensity fitting active surface and alpha matting","display_name":"Unsupervised tumour segmentation in PET based on local and global intensity fitting active surface and alpha matting","publication_year":2012,"publication_date":"2012-08-01","ids":{"openalex":"https://openalex.org/W1974632212","doi":"https://doi.org/10.1109/embc.2012.6346432","mag":"1974632212","pmid":"https://pubmed.ncbi.nlm.nih.gov/23366393"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2012.6346432","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346432","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105259106","display_name":"Ziming Zeng","orcid":null},"institutions":[{"id":"https://openalex.org/I16038530","display_name":"Aberystwyth University","ror":"https://ror.org/015m2p889","country_code":"GB","type":"education","lineage":["https://openalex.org/I16038530"]},{"id":"https://openalex.org/I83714178","display_name":"Shenyang Jianzhu University","ror":"https://ror.org/01zr73v18","country_code":"CN","type":"education","lineage":["https://openalex.org/I83714178"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Ziming Zeng","raw_affiliation_strings":["Faculty of Information and Control Engineering, Shenyang Jianzhu University, Shenyang, China. zzz09@aber.ac.uk","Faculty of Information and Control Engineering, Shenyang Jianzhu University, Shenyang, China","Department of Computer Science, Aberystwyth University, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Information and Control Engineering, Shenyang Jianzhu University, Shenyang, China. zzz09@aber.ac.uk","institution_ids":["https://openalex.org/I83714178"]},{"raw_affiliation_string":"Faculty of Information and Control Engineering, Shenyang Jianzhu University, Shenyang, China","institution_ids":["https://openalex.org/I83714178"]},{"raw_affiliation_string":"Department of Computer Science, Aberystwyth University, UK","institution_ids":["https://openalex.org/I16038530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111536787","display_name":"Thomas Shepherd","orcid":null},"institutions":[{"id":"https://openalex.org/I2801970007","display_name":"Turku University Hospital","ror":"https://ror.org/05dbzj528","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2801970007","https://openalex.org/I4210127022"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"T. Shepherd","raw_affiliation_strings":["Turku PET Center and Department of Oncology and Radiotherapy, Turku University Hospital, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Turku PET Center and Department of Oncology and Radiotherapy, Turku University Hospital, Finland","institution_ids":["https://openalex.org/I2801970007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075394907","display_name":"Reyer Zwiggelaar","orcid":"https://orcid.org/0000-0002-4360-0896"},"institutions":[{"id":"https://openalex.org/I16038530","display_name":"Aberystwyth University","ror":"https://ror.org/015m2p889","country_code":"GB","type":"education","lineage":["https://openalex.org/I16038530"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R. Zwiggelaar","raw_affiliation_strings":["Department of Computer Science, Aberystwyth University, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Aberystwyth University, UK","institution_ids":["https://openalex.org/I16038530"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5128,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.68979482,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"5241","issue":null,"first_page":"2339","last_page":"2342"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.8347979784011841},{"id":"https://openalex.org/keywords/subpixel-rendering","display_name":"Subpixel rendering","score":0.7841957807540894},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7135711908340454},{"id":"https://openalex.org/keywords/imaging-phantom","display_name":"Imaging phantom","score":0.6367270946502686},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6243845224380493},{"id":"https://openalex.org/keywords/partial-volume","display_name":"Partial volume","score":0.6222800016403198},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.6165271401405334},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.574149489402771},{"id":"https://openalex.org/keywords/volume","display_name":"Volume (thermodynamics)","score":0.477411150932312},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4729180932044983},{"id":"https://openalex.org/keywords/alpha","display_name":"Alpha (finance)","score":0.46993571519851685},{"id":"https://openalex.org/keywords/scale-space-segmentation","display_name":"Scale-space segmentation","score":0.46873077750205994},{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.25323325395584106},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1845380663871765},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.16216403245925903},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.06712308526039124}],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.8347979784011841},{"id":"https://openalex.org/C68516990","wikidata":"https://www.wikidata.org/wiki/Q452912","display_name":"Subpixel rendering","level":3,"score":0.7841957807540894},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7135711908340454},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.6367270946502686},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6243845224380493},{"id":"https://openalex.org/C82233179","wikidata":"https://www.wikidata.org/wiki/Q2054500","display_name":"Partial volume","level":2,"score":0.6222800016403198},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.6165271401405334},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.574149489402771},{"id":"https://openalex.org/C20556612","wikidata":"https://www.wikidata.org/wiki/Q4469374","display_name":"Volume (thermodynamics)","level":2,"score":0.477411150932312},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4729180932044983},{"id":"https://openalex.org/C64943373","wikidata":"https://www.wikidata.org/wiki/Q2651003","display_name":"Alpha (finance)","level":4,"score":0.46993571519851685},{"id":"https://openalex.org/C65885262","wikidata":"https://www.wikidata.org/wiki/Q7429708","display_name":"Scale-space segmentation","level":4,"score":0.46873077750205994},{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.25323325395584106},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1845380663871765},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.16216403245925903},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06712308526039124},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C49453240","wikidata":"https://www.wikidata.org/wiki/Q1592163","display_name":"Construct validity","level":3,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C171606756","wikidata":"https://www.wikidata.org/wiki/Q506132","display_name":"Psychometrics","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2012.6346432","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346432","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:23366393","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23366393","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1500378594","https://openalex.org/W1605048340","https://openalex.org/W1973169445","https://openalex.org/W2005967953","https://openalex.org/W2035773017","https://openalex.org/W2038210795","https://openalex.org/W2038495454","https://openalex.org/W2077447874","https://openalex.org/W2082722708","https://openalex.org/W2090873345","https://openalex.org/W2163622677","https://openalex.org/W4321317560","https://openalex.org/W6652084517"],"related_works":["https://openalex.org/W2310453852","https://openalex.org/W2185902295","https://openalex.org/W2103507220","https://openalex.org/W3144569342","https://openalex.org/W2945274617","https://openalex.org/W4313052709","https://openalex.org/W2143795300","https://openalex.org/W4205800335","https://openalex.org/W2055202857","https://openalex.org/W2022929107"],"abstract_inverted_index":{"This":[0],"paper":[1],"proposes":[2],"an":[3,45],"unsupervised":[4],"tumour":[5],"segmentation":[6,59,93],"scheme":[7],"for":[8],"PET":[9,68,82],"data.":[10],"The":[11],"method":[12,48,65,88],"computes":[13],"the":[14,24,58],"volume":[15,29],"of":[16,70,78],"interests":[17],"(VOIs)":[18],"with":[19,96],"subpixel":[20],"precision":[21],"by":[22],"considering":[23],"limited":[25],"resolution":[26],"and":[27,35,56],"partial":[28],"effect.":[30],"Firstly,":[31],"it":[32],"uses":[33],"local":[34],"global":[36],"intensity":[37],"active":[38],"surface":[39],"modelling":[40],"to":[41,51],"segment":[42],"VOIs,":[43],"then":[44],"alpha":[46],"matting":[47],"is":[49],"used":[50],"eliminate":[52],"false":[53],"negative":[54],"classification":[55],"refine":[57],"results.":[60],"We":[61],"have":[62],"validated":[63],"our":[64,87],"on":[66],"real":[67],"images":[69,77],"head-and-neck":[71],"cancer":[72],"patients":[73],"as":[74,76],"well":[75],"a":[79],"custom":[80],"designed":[81],"phantom.":[83],"Experiments":[84],"show":[85],"that":[86],"can":[89],"generate":[90],"more":[91],"accurate":[92],"results":[94],"compared":[95],"alternative":[97],"approaches.":[98]},"counts_by_year":[{"year":2013,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}