INTS9

INTS9
Identifikatori
Aliasi	INTS9
Vanjski ID-jevi	OMIM: 611352 MGI: 1098533 HomoloGene: 10096 GeneCards: INTS9
Lokacija gena (čovjek)
Hrom.	Hromosom 8 (čovjek)
Kraj	28,890,242 bp
Lokacija gena (miš)
Hrom.	Hromosom 14 (miš)
Kraj	65,277,284 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• integrator complex; • nukleoplazma; • citosol; • jedro;
Biološki proces	• snRNA processing; • snRNA transcription by RNA polymerase II;
	Izvori:Amigo / QuickGO
Ortolozi
	55756
	210925
	ENSG00000104299
	ENSMUSG00000021975
	Q9NV88
	Q8K114
	NM_001145159; NM_001172562; NM_018250; NM_001363038
	NM_001253731; NM_153414
	NP_001138631; NP_001166033; NP_060720; NP_001349967
	NP_001240660; NP_700463
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Podjedinica 9 integratorskog kompleksa je protein koji je kod ljudi kodiran genom INTS9.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 658 aminokiselina, а molekulska težina 73.814 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MKLYCLSGHP	TLPCNVLKFK	STTIMLDCGL	DMTSTLNFLP	LPLVQSPRLS
NLPGWSLKDG	NAFLDKELKE	CSGHVFVDSV	PEFCLPETEL	IDLSTVDVIL
ISNYHCMMAL	PYITEHTGFT	GTVYATEPTV	QIGRLLMEEL	VNFIERVPKA
QSASLWKNKD	IQRLLPSPLK	DAVEVSTWRR	CYTMQEVNSA	LSKIQLVGYS
QKIELFGAVQ	VTPLSSGYAL	GSSNWIIQSH	YEKVSYVSGS	SLLTTHPQPM
DQASLKNSDV	LVLTGLTQIP	TANPDGMVGE	FCSNLALTVR	NGGNVLVPCY
PSGVIYDLLE	CLYQYIDSAG	LSSVPLYFIS	PVANSSLEFS	QIFAEWLCHN
KQSKVYLPEP	PFPHAELIQT	NKLKHYPSIH	GDFSNDFRQP	CVVFTGHPSL
RFGDVVHFME	LWGKSSLNTV	IFTEPDFSYL	EALAPYQPLA	MKCIYCPIDT
RLNFIQVSKL	LKEVQPLHVV	CPEQYTQPPP	AQSHRMDLMI	DCQPPAMSYR
RAEVLALPFK	RRYEKIEIMP	ELADSLVPME	IKPGISLATV	SAVLHTKDNK
HLLQPPPRPA	QPTSGKKRKR	VSDDVPDCKV	LKPLLSGSIP	VEQFVQTLEK
HGFSDIKVED	TAKGHIVLLQ	EAETLIQIEE	DSTHIICDND	EMLRVRLRDL
VLKFLQKF

Reference

1 2 3 GRCh38: Ensembl release 89: ENSG00000104299 - Ensembl, maj 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021975 - Ensembl, maj 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi:10.1016/j.cell.2005.08.019. PMID 16239144. S2CID 18069461.
↑ "Entrez Gene: RC74 integrator complex subunit 9".
↑ "UniProt, Q9NV88" (jezik: engleski). Pristupljeno 19. 9. 2021.

Dopunska literatura

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Dominski Z, Yang XC, Purdy M, et al. (2005). "A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100". Mol. Cell. Biol. 25 (4): 1489–500. doi:10.1128/MCB.25.4.1489-1500.2005. PMC 548002. PMID 15684398.
Nusbaum C, Mikkelsen TS, Zody MC, et al. (2006). "DNA sequence and analysis of human chromosome 8". Nature. 439 (7074): 331–5. Bibcode:2006Natur.439..331N. doi:10.1038/nature04406. PMID 16421571.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000104299 - Ensembl, maj 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021975 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16239144-5] Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi:10.1016/j.cell.2005.08.019. PMID 16239144. S2CID 18069461.

[entrez-6] "Entrez Gene: RC74 integrator complex subunit 9".

[UniProt-7] "UniProt, Q9NV88" (jezik: engleski). Pristupljeno 19. 9. 2021.

[1]

[2]

[3]

[4]

[5]

[6]

[7]