A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.

Donna Arnett Donna K. Arnett

Xihao Li Han Chen Margaret Sunitha Selvaraj Eric Van Buren Hufeng Zhou Yuxuan Wang 0008 Ryan Sun Zachary R. McCaw Zhi Yu Min-Zhi Jiang Daniel DiCorpo Sheila M. Gaynor Rounak Dey Donna K. Arnett Emelia J. Benjamin Joshua C. Bis John Blangero Eric Boerwinkle Donald W. Bowden Jennifer A. Brody Brian E. Cade April P. Carson Jenna C. Carlson Nathalie Chami Yii-Der Ida Chen Joanne E. Curran Paul S. de Vries Myriam Fornage Nora Franceschini Barry I. Freedman Charles Gu Nancy L. Heard-Costa Jiang He Lifang Hou Yi-Jen Hung Marguerite R. Irvin Robert C. Kaplan Sharon L. R. Kardia Tanika N. Kelly Iain R. Konigsberg Charles L. Kooperberg Brian G. Kral Changwei Li Yun Li Honghuang Lin Ching-Ti Liu Ruth J. F. Loos Michael C. Mahaney Lisa W. Martin Rasika A. Mathias Braxton D. Mitchell May E. Montasser Alanna C. Morrison Take Naseri Kari E. North Nicholette D. Palmer Patricia A. Peyser Bruce M. Psaty Susan Redline Alexander P. Reiner Stephen S. Rich Colleen M. Sitlani Jennifer A. Smith Kent D. Taylor Hemant K. Tiwari Ramachandran S. Vasan Satupa'itea Viali Zhe Wang Jennifer Wessel Lisa R. Yanek Bing Yu NHLBI Trans-Omics for Precision Medicine Consortium Josée Dupuis James B. Meigs Paul L. Auer Laura M. Raffield Alisa K. Manning Kenneth M. Rice Jerome I. Rotter Gina M. Peloso Pradeep Natarajan Zilin Li Zhonghua Liu Xihong Lin A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies. 125-143 2025 February 5 Nat. Comput. Sci. 2 https://doi.org/10.1038/s43588-024-00764-8 db/journals/ncs/ncs5.html#LiCSBZWSMYJDGDABBBBBBCC25 streams/journals/ncs

Yiming Li Sanjiv J. Shah Donna Arnett Ryan Irvin Yuan Luo 0001 SNPs Filtered by Allele Frequency Improve the Prediction of Hypertension Subtypes. 2796-2802 2021 BIBM https://doi.org/10.1109/BIBM52615.2021.9669758 conf/bibm/2021 db/conf/bibm/bibm2021.html#LiSAI021

Yiming Li Sanjiv J. Shah Donna Arnett Ryan Irvin Yuan Luo 0001 SNPs Filtered by Allele Frequency Improve the Prediction of Hypertension Subtypes. 2021 abs/2111.10471 CoRR https://arxiv.org/abs/2111.10471 db/journals/corr/corr2111.html#abs-2111-10471

Yuan Luo 0001 Chengsheng Mao Yiben Yang Fei Wang 0001 Faraz S. Ahmad Donna Arnett Marguerite R. Irvin Sanjiv J. Shah Integrating hypertension phenotype and genotype with hybrid non-negative matrix factorization. 1395-1403 2019 35 Bioinform. 8 https://doi.org/10.1093/bioinformatics/bty804 https://www.wikidata.org/entity/Q91617679 db/journals/bioinformatics/bioinformatics35.html#LuoMYWAAIS19

Yuan Luo 0001 Chengsheng Mao Yiben Yang Fei Wang 0001 Faraz S. Ahmad Donna Arnett Marguerite R. Irvin Sanjiv J. Shah Integrating hypertension phenotype and genotype with hybrid non-negative matrix factorization. 2885 2019 35 Bioinform. 16 https://doi.org/10.1093/bioinformatics/btz049 https://www.wikidata.org/entity/Q91501178 db/journals/bioinformatics/bioinformatics35.html#LuoMYWAAIS19a

Yuan Luo 0001 Chengsheng Mao Yiben Yang Fei Wang 0001 Faraz S. Ahmad Donna Arnett Marguerite R. Irvin Sanjiv J. Shah Integrating Hypertension Phenotype and Genotype with Hybrid Non-negative Matrix Factorization. 102-118 2018 MLHC http://proceedings.mlr.press/v85/luo18a.html conf/mlhc/2018 db/conf/mlhc/mlhc2018.html#LuoMYWAAIS18

Yuan Luo 0001 Chengsheng Mao Yiben Yang Fei Wang 0001 Faraz S. Ahmad Donna Arnett Marguerite R. Irvin Sanjiv J. Shah Integrating Hypertension Phenotype and Genotype with Hybrid Non-negative Matrix Factorization. 2018 abs/1805.05008 CoRR http://arxiv.org/abs/1805.05008 db/journals/corr/corr1805.html#abs-1805-05008

Faraz S. Ahmad Paul L. Auer Emelia J. Benjamin Joshua C. Bis John Blangero Eric Boerwinkle Donald W. Bowden Jennifer A. Brody Eric Van Buren Brian E. Cade Jenna C. Carlson April P. Carson Nathalie Chami Han Chen Yii-Der Ida Chen NHLBI Trans-Omics for Precision Medicine Consortium Joanne E. Curran Rounak Dey Daniel DiCorpo Josée Dupuis Myriam Fornage Nora Franceschini Barry I. Freedman Sheila M. Gaynor Charles Gu Jiang He Nancy L. Heard-Costa Lifang Hou Yi-Jen Hung Marguerite R. Irvin Ryan Irvin Min-Zhi Jiang Robert C. Kaplan Sharon L. R. Kardia Tanika N. Kelly Iain R. Konigsberg Charles L. Kooperberg Brian G. Kral Changwei Li Xihao Li Yiming Li Yun Li Zilin Li Honghuang Lin Xihong Lin Ching-Ti Liu Zhonghua Liu Ruth J. F. Loos Yuan Luo 0001 Michael C. Mahaney Alisa ManningAlisa K. Manning Chengsheng Mao Lisa W. Martin Rasika A. Mathias Zachary R. McCaw James B. Meigs Braxton D. Mitchell May E. Montasser Alanna C. Morrison Take Naseri Pradeep Natarajan Kari E. North Nicholette D. Palmer Gina M. Peloso Patricia A. Peyser Bruce M. Psaty Laura M. Raffield Susan Redline Alex P. ReinerAlexander P. Reiner Ken RiceKenneth M. Rice Stephen S. Rich Jerome I. Rotter Margaret Sunitha Selvaraj Sanjiv J. Shah Colleen M. Sitlani Jennifer A. Smith Ryan Sun Kent D. Taylor Hemant K. Tiwari Ramachandran S. Vasan Satupa'itea Viali Paul S. de Vries Fei Wang 0001 Yuxuan Wang 0008 Zhe Wang Jennifer Wessel Lisa R. Yanek Yiben Yang Bing Yu Zhi Yu Hufeng Zhou