Localizing Synergies of Hidden Factors in Complex Systems: Resting Brain Networks and HeLa GeneExpression Profile as Case Studies.

Sebastiano Stramaglia https://zbmath.org/authors/?q=ai:stramaglia.sebastiano https://orcid.org/0000-0002-5873-8564 https://www.wikidata.org/entity/Q56994306 https://d-nb.info/gnd/1128676931 https://id.loc.gov/authorities/names/no2002092404

Marlis Ontivero-Ortega Gorana Mijatovic Luca Faes Fernando E. Rosas Daniele Marinazzo Sebastiano Stramaglia Localizing Synergies of Hidden Factors in Complex Systems: Resting Brain Networks and HeLa GeneExpression Profile as Case Studies. 820 2025 27 Entropy 8 https://doi.org/10.3390/e27080820 db/journals/entropy/entropy27.html#OntiveroOrtegaMFRMS25 streams/journals/entropy

Gorana Mijatovic Sebastiano Stramaglia Luca Faes A Model-Free Method to Quantify Memory Utilization in Neural Point Processes. 2532-2543 2025 August 72 IEEE Trans. Biomed. Eng. 8 https://doi.org/10.1109/TBME.2025.3546842 db/journals/tbe/tbe72.html#MijatovicSF25 streams/journals/tbe

Gorana Mijatovic Yuri Antonacci Michal Javorka Daniele Marinazzo Sebastiano Stramaglia Luca Faes Network Representation of Higher-Order Interactions Based on Information Dynamics. 1872-1884 2025 May - June 12 IEEE Trans. Netw. Sci. Eng. 3 https://doi.org/10.1109/TNSE.2025.3540982 db/journals/tnse/tnse12.html#MijatovicAJMSF25 streams/journals/tnse

Marta Iovino Marlis Ontivero-Ortega Chiara Barà Sebastiano Stramaglia Michal Javorka Riccardo Pernice Luca Faes Assessing Feature Importance in Cardiovascular Variability for the Classification of Physiological Stress. 1-6 2025 COINS https://doi.org/10.1109/COINS65080.2025.11125740 conf/coins/2025 db/conf/coins/coins2025.html#IovinoOBSJPF25 streams/conf/coins

Laura Sparacino Gorana Mijatovic Yuri Antonacci Leonardo Ricci Daniele Marinazzo Sebastiano Stramaglia Luca Faes Decomposing Multivariate Information Rates in Networks of Random Processes. 2025 February abs/2502.04555 CoRR https://doi.org/10.48550/arXiv.2502.04555 db/journals/corr/corr2502.html#abs-2502-04555 streams/journals/corr

Ivan Lazic Chiara Barà Marta Iovino Sebastiano Stramaglia Niksa Jakovljevic Luca Faes Information-theoretic Quantification of High-order Feature Effects in Classification Problems. 2025 July abs/2507.04362 CoRR https://doi.org/10.48550/arXiv.2507.04362 db/journals/corr/corr2507.html#abs-2507-04362 streams/journals/corr

Marlis Ontivero-Ortega Alessandro Fania Antonio Lacalamita Roberto Bellotti Alfonso Monaco Sebastiano Stramaglia Cooperative effects in feature importance of individual patterns: application to air pollutants and Alzheimer disease. 2025 August abs/2508.00930 CoRR https://doi.org/10.48550/arXiv.2508.00930 db/journals/corr/corr2508.html#abs-2508-00930 streams/journals/corr

Jerry Jones David Narayan G. Sabhahit Sebastiano Stramaglia T. Di Matteo Stefano Boccaletti Sarika Jalan Functional Hypergraphs of Stock Markets. 848 2024 26 Entropy 10 https://doi.org/10.3390/e26100848 db/journals/entropy/entropy26.html#DavidSSMBJ24 streams/journals/entropy

Kenzo Clauw Sebastiano Stramaglia Daniele Marinazzo Information-Theoretic Progress Measures reveal Grokking is an Emergent Phase Transition. 2024 abs/2408.08944 CoRR https://doi.org/10.48550/arXiv.2408.08944 db/journals/corr/corr2408.html#abs-2408-08944 streams/journals/corr

Luca Faes Gorana Mijatovic Laura Sparacino Yuri Antonacci Daniele Marinazzo Sebastiano Stramaglia Investigating Dynamic High-Order Interactions in Physiological Networks through Predictive Information Decomposition. 1-4 2023 EMBC https://doi.org/10.1109/EMBC40787.2023.10340690 conf/embc/2023 db/conf/embc/embc2023.html#FaesMSAMS23

Gorana Mijatovic Dragan Kljajic Karolina K. Kasas-Lazetic Miodrag Milutinov Salvatore Stivala Alessandro Busacca Alfonso C. Cino Sebastiano Stramaglia Luca Faes Information Dynamics of Electric Field Intensity before and during the COVID-19 Pandemic. 726 2022 24 Entropy 5 https://doi.org/10.3390/e24050726 db/journals/entropy/entropy24.html#MijatovicKKMSBC22

Luca Faes Gorana Mijatovic Yuri Antonacci Riccardo Pernice Chiara Barà Laura Sparacino Marco Sammartino Alberto Porta Daniele Marinazzo Sebastiano Stramaglia A New Framework for the Time- and Frequency-Domain Assessment of High-Order Interactions in Networks of Random Processes. 5766-5777 2022 70 IEEE Trans. Signal Process. https://doi.org/10.1109/TSP.2022.3221892 db/journals/tsp/tsp70.html#FaesMAPBSSPMS22

Laura Sparacino Yuri Antonacci Daniele Marinazzo Sebastiano Stramaglia Luca Faes Quantifying High-Order Interactions in Complex Physiological Networks: A Frequency-Specific Approach. 301-309 2022 COMPLEX NETWORKS (1) https://doi.org/10.1007/978-3-031-21127-0_25 conf/complexnetworks/2022-1 db/conf/complexnetworks/complexnetworks2022-1.html#SparacinoAMSF22

Fernando E. Rosas Pedro A. M. Mediano Andrea I. Luppi Thomas F. Varley Joseph T. Lizier Sebastiano Stramaglia Henrik J. Jensen Daniele Marinazzo Disentangling high-order mechanisms and high-order behaviours in complex systems. 2022 abs/2203.12041 CoRR https://doi.org/10.48550/arXiv.2203.12041 db/journals/corr/corr2203.html#abs-2203-12041

Tomas Scagliarini Davide Nuzzi Yuri Antonacci Luca Faes Fernando E. Rosas Daniele Marinazzo Sebastiano Stramaglia Gradients of O-information: low-order descriptors of high-order dependencies. 2022 abs/2207.03581 CoRR https://doi.org/10.48550/arXiv.2207.03581 db/journals/corr/corr2207.html#abs-2207-03581

Kenzo Clauw Sebastiano Stramaglia Daniele Marinazzo Higher-order mutual information reveals synergistic sub-networks for multi-neuron importance. 2022 abs/2211.00416 CoRR https://doi.org/10.48550/arXiv.2211.00416 db/journals/corr/corr2211.html#abs-2211-00416

Yuri Antonacci Ludovico Minati Davide Nuzzi Gorana Mijatovic Riccardo Pernice Daniele Marinazzo Sebastiano Stramaglia Luca Faes Measuring High-Order Interactions in Rhythmic Processes Through Multivariate Spectral Information Decomposition. 149486-149505 2021 9 IEEE Access https://doi.org/10.1109/ACCESS.2021.3124601 db/journals/access/access9.html#AntonacciMNMPMS21

Maider Nuñez-Ibero Borja Camino-Pontes Ibai Díez Asier Erramuzpe Endika Martinez-Gutierrez Sebastiano Stramaglia Javier O. Alvarez-Cienfuegos Jesús M. Cortés A Controlled Thermoalgesic Stimulation Device for Exploring Novel Pain Perception Biomarkers. 2948-2957 2021 25 IEEE J. Biomed. Health Informatics 8 https://doi.org/10.1109/JBHI.2021.3080935 db/journals/titb/titb25.html#Nunez-IberoCDEM21

Tomas Scagliarini Luca Faes Daniele Marinazzo Sebastiano Stramaglia Rosario N. Mantegna Synergistic Information Transfer in the Global System of Financial Markets. 1000 2020 22 Entropy 9 https://doi.org/10.3390/e22091000 https://www.wikidata.org/entity/Q104108239 db/journals/entropy/entropy22.html#ScagliariniFMSM20

Davide Nuzzi Luca Faes Michal Javorka Daniele Marinazzo Sebastiano Stramaglia Inclusion of Instantaneous Influences in the Spectral Decomposition of Causality: Application to the Control Mechanisms of Heart Rate Variability. 930-934 2020 EUSIPCO https://doi.org/10.23919/Eusipco47968.2020.9287642 conf/eusipco/2020 db/conf/eusipco/eusipco2020.html#NuzziFJMS20

Lucas Lacasa Sebastiano Stramaglia Daniele Marinazzo Beyond pairwise network similarity: exploring Mediation and Suppression between networks. 2020 abs/2012.09006 CoRR https://arxiv.org/abs/2012.09006 db/journals/corr/corr2012.html#abs-2012-09006

Jana Krohova Luca Faes Barbora Czippelova Zuzana Turianikova Nikoleta Mazgutova Riccardo Pernice Alessandro Busacca Daniele Marinazzo Sebastiano Stramaglia Michal Javorka Multiscale Information Decomposition Dissects Control Mechanisms of Heart Rate Variability at Rest and During Physiological Stress. 526 2019 21 Entropy 5 https://doi.org/10.3390/e21050526 https://www.wikidata.org/entity/Q103833405 db/journals/entropy/entropy21.html#KrohovaFCTMPBMS19

Borja Camino-Pontes Ibai Díez Antonio Jimenez-Marin Javier Rasero Asier Erramuzpe Paolo Bonifazi Sebastiano Stramaglia Stephan P. Swinnen Jesús M. Cortés Interaction Information Along Lifespan of the Resting Brain Dynamics Reveals a Major Redundant Role of the Default Mode Network. 742 2018 20 Entropy 10 https://doi.org/10.3390/e20100742 https://www.wikidata.org/entity/Q103830997 db/journals/entropy/entropy20.html#Camino-PontesDJ18

Luca Faes Daniele Marinazzo Sebastiano Stramaglia Multiscale Information Decomposition: Exact Computation for Multivariate Gaussian Processes. 408 2017 19 Entropy 8 https://doi.org/10.3390/e19080408 https://www.wikidata.org/entity/Q57894004 db/journals/entropy/entropy19.html#FaesMS17

Sebastiano Stramaglia Iege Bassez Luca Faes Daniele Marinazzo Multiscale Granger causality analysis by à trous wavelet transform. 25-28 2017 IWASI https://doi.org/10.1109/IWASI.2017.7974204 conf/iwasi/2017 db/conf/iwasi/iwasi2017.html#StramagliaBFM17

Julia M. Kroos Ibai Díez Jesús M. Cortés Sebastiano Stramaglia Luca Gerardo-Giorda Geometry Shapes Propagation: Assessing the Presence and Absence of Cortical Symmetries through a Computational Model of Cortical Spreading Depression. 2016 10 Frontiers Comput. Neurosci. https://doi.org/10.3389/fncom.2016.00006 https://www.wikidata.org/entity/Q42129926 db/journals/ficn/ficn10.html#KroosDCSG16 6

Sebastiano Stramaglia Leonardo Angelini Guorong Wu 0003 Jesús M. Cortés Luca Faes Daniele Marinazzo Synergetic and Redundant Information Flow Detected by Unnormalized Granger Causality: Application to Resting State fMRI. 2518-2524 2016 63 IEEE Trans. Biomed. Eng. 12 https://doi.org/10.1109/TBME.2016.2559578 https://www.wikidata.org/entity/Q38766937 db/journals/tbe/tbe63.html#StramagliaAWCFM16

Luca Faes Alessandro Montalto Sebastiano Stramaglia Giandomenico Nollo Daniele Marinazzo Multiscale analysis of information dynamics for linear multivariate processes. 5489-5492 2016 EMBC https://doi.org/10.1109/EMBC.2016.7591969 https://www.wikidata.org/entity/Q50857143 conf/embc/2016 db/conf/embc/embc2016.html#FaesMSNM16

Luca Faes Alessandro Montalto Sebastiano Stramaglia Giandomenico Nollo Daniele Marinazzo Multiscale Analysis of Information Dynamics for Linear Multivariate Processes. 2016 abs/1602.06155 CoRR http://arxiv.org/abs/1602.06155 db/journals/corr/corr1602.html#FaesMSNM16

Ibai Díez Asier Erramuzpe Iñaki Escudero Beatriz Mateos Alberto Cabrera Daniele Marinazzo Ernesto J. Sanz-Arigita Sebastiano Stramaglia Jesús M. Cortés Diaz Information Flow Between Resting-State Networks. 554-564 2015 5 Brain Connect. 9 https://doi.org/10.1089/brain.2014.0337 https://www.wikidata.org/entity/Q36297905 db/journals/brain/brain5.html#DiezEEMCMSSD15

Alessandro Montalto Sebastiano Stramaglia Luca Faes Giovanni Tessitore Roberto Prevete Daniele Marinazzo Neural networks with non-uniform embedding and explicit validation phase to assess Granger causality. 159-171 2015 71 Neural Networks https://doi.org/10.1016/j.neunet.2015.08.003 https://www.wikidata.org/entity/Q38965483 db/journals/nn/nn71.html#MontaltoSFTPM15

Sebastiano Stramaglia Leonardo Angelini Jesús M. Cortés Daniele Marinazzo Synergy, redundancy and unnormalized Granger causality. 4037-4040 2015 EMBC https://doi.org/10.1109/EMBC.2015.7319280 https://www.wikidata.org/entity/Q40138138 conf/embc/2015 db/conf/embc/embc2015.html#StramagliaACM15

Sebastiano Stramaglia Leonardo Angelini Jesús M. Cortés Daniele Marinazzo Synergy, redundancy and unnormalized Granger causality. 2015 abs/1504.03584 CoRR http://arxiv.org/abs/1504.03584 db/journals/corr/corr1504.html#StramagliaACM15

Asier Erramuzpe J. M. Encinas Amanda Sierra Mirjana Maletic-Savatic A. L. Brewster Anne E. Anderson Sebastiano Stramaglia Jesús M. Cortés Longitudinal variations of brain functional connectivity: A case report study based on a mouse model of epilepsy. 144 2015 4 F1000Research https://doi.org/10.12688/f1000research.6570.1 https://www.wikidata.org/entity/Q125388747 db/journals/f1000research/f1000research4.html#ErramuzpeESMBASC15

Sebastiano Stramaglia Jesús M. Cortés Daniele Marinazzo Synergy and redundancy in the Granger causal analysis of dynamical networks. 2014 abs/1403.5156 CoRR http://arxiv.org/abs/1403.5156 db/journals/corr/corr1403.html#StramagliaCM14

Guo-Rong Wu 0003 Wei Liao 0001 Sebastiano Stramaglia Huafu Chen Daniele Marinazzo Recovering Directed Networks in Neuroimaging Datasets Using Partially Conditioned Granger Causality. 294-301 2013 3 Brain Connect. 3 https://doi.org/10.1089/brain.2013.0142 https://www.wikidata.org/entity/Q42161454 db/journals/brain/brain3.html#WuLSCM13

Guo-Rong Wu 0003 Wei Liao 0001 Sebastiano Stramaglia Jurong Ding Huafu Chen Daniele Marinazzo A blind deconvolution approach to recover effective connectivity brain networks from resting state fMRI data. 365-374 2013 17 Medical Image Anal. 3 https://doi.org/10.1016/j.media.2013.01.003 https://www.wikidata.org/entity/Q30591020 db/journals/mia/mia17.html#WuLSDCM13

Gabriele Trotta Sebastiano Stramaglia Mario Pellicoro Roberto Bellotti Daniele Marinazzo Marina de Tommaso Effective connectivity and cortical information flow under visual stimulation in migraine with aura. 228-232 2013 IWASI https://doi.org/10.1109/IWASI.2013.6576076 https://www.wikidata.org/entity/Q58342921 conf/iwasi/2013 db/conf/iwasi/iwasi2013.html#TrottaSPBMT13

Daniele Marinazzo Mario Pellicoro Sebastiano Stramaglia Causal Information Approach to Partial Conditioning in Multivariate Data Sets. 2012 2012 Comput. Math. Methods Medicine https://doi.org/10.1155/2012/303601 https://www.wikidata.org/entity/Q34295393 db/journals/cmmm/cmmm2012.html#MarinazzoPS12 303601:1-303601:8

Sebastiano Stramaglia Guo-Rong Wu 0003 Mario Pellicoro Daniele Marinazzo Expanding the transfer entropy to identify information subgraphs in complex systems. 3668-3671 2012 EMBC https://doi.org/10.1109/EMBC.2012.6346762 https://www.wikidata.org/entity/Q39475668 conf/embc/2012 db/conf/embc/embc2012.html#StramagliaWPM12 Guorong Wu 0003 Sebastiano Stramaglia Daniele Marinazzo Decomposition of the Transfer Entropy: Partial Conditioning and Informative Clustering. 226-233 2012 ICONIP (1) https://doi.org/10.1007/978-3-642-34475-6_28 conf/iconip/2012-1 db/conf/iconip/iconip2012-1.html#WuSM12

Daniele Marinazzo Mario Pellicoro Guo-Rong Wu 0003 Leonardo Angelini Sebastiano Stramaglia Information flow in a network model and the law of diminishing marginal returns http://arxiv.org/abs/1202.5041 2012 CoRR abs/1202.5041 db/journals/corr/corr1202.html#abs-1202-5041

Sebastiano Stramaglia Guo-Rong Wu 0003 Mario Pellicoro Daniele Marinazzo Expanding the Transfer Entropy to Identify Information Subgraphs in Complex Systems http://arxiv.org/abs/1203.3037 2012 CoRR abs/1203.3037 db/journals/corr/corr1203.html#abs-1203-3037

Daniele Marinazzo Wei Liao 0001 Huafu Chen Sebastiano Stramaglia Nonlinear connectivity by Granger causality. 330-338 2011 58 NeuroImage 2 https://doi.org/10.1016/j.neuroimage.2010.01.099 https://www.wikidata.org/entity/Q33529517 db/journals/neuroimage/neuroimage58.html#MarinazzoLCS11

Leonardo Angelini Daniele Marinazzo Mario Pellicoro Sebastiano Stramaglia Semi-supervised learning by search of optimal target vector. 34-39 2008 29 Pattern Recognit. Lett. 1 https://doi.org/10.1016/j.patrec.2007.08.010 db/journals/prl/prl29.html#AngeliniMPS08

Leonardo Angelini Roberto Maestri Daniele Marinazzo Luigi Nitti Mario Pellicoro Gian Domenico Pinna Sebastiano Stramaglia Salvatore A. Tupputi Multiscale analysis of short term heart beat interval, arterial blood pressure, and instantaneous lung volume time series. 237-250 2007 41 Artif. Intell. Medicine 3 https://doi.org/10.1016/j.artmed.2007.07.012 https://www.wikidata.org/entity/Q48378638 db/journals/artmed/artmed41.html#AngeliniMMNPPST07

Leonardo Angelini Daniele Marinazzo Mario Pellicoro Sebastiano Stramaglia Causality and communities in neural networks. 459-464 2007 ESANN https://www.esann.org/sites/default/files/proceedings/legacy/es2007-26.pdf conf/esann/2007 db/conf/esann/esann2007.html#AngeliniMPS07

Nicola Ancona Sebastiano Stramaglia An Invariance Property of Predictors in Kernel-Induced Hypothesis Spaces. 749-759 2006 18 Neural Comput. 4 https://doi.org/10.1162/neco.2006.18.4.749 https://www.wikidata.org/entity/Q52025309 db/journals/neco/neco18.html#AnconaS06

Daniele Marinazzo Mario Pellicoro Sebastiano Stramaglia Nonlinear parametric model for Granger causality of time series http://arxiv.org/abs/cond-mat/0602183 2006 CoRR abs/cond-mat/0602183 db/journals/corr/corr0602.html#abs-cond-mat-0602183

Fabio Bovenga Sebastiano Stramaglia Raffaele Nutricato Alberto Refice Discrimination of different sources of signals in permanent scatterers technique by means of independent component analysis. 2103-2105 2003 IGARSS https://doi.org/10.1109/IGARSS.2003.1294353 conf/igarss/2003 db/conf/igarss/igarss2003.html#BovengaSNR03 Alberto Refice Fabio Bovenga Sebastiano Stramaglia Domenico Conte Use of scaling information for stochastic atmospheric absolute phase screen retrieval. 1729-1731 2002 IGARSS https://doi.org/10.1109/IGARSS.2002.1026235 conf/igarss/2002 db/conf/igarss/igarss2002.html#ReficeBSC02 Fabio Bovenga Alberto Refice Sebastiano Stramaglia Domenico Conte Phase unwrapping by means of scaling information and global optimization algorithms. 0000 2002 SAR https://doi.org/10.1117/12.463178 conf/sar/2002 db/conf/sar/sar2002.html#BovengaRSC02

Armando Sternieri P. Anelli Sebastiano Stramaglia U. Emiliani AGAPE: Parallel Genetic Algorithm Programming Environment Developed for ape100/quadrics. 1999 18 Comput. Artif. Intell. 3 db/journals/cai/cai18.html#SternieriASE99 http://www.cai.sk/ojs/index.php/cai/article/view/599 217-237

Sebastiano Stramaglia Guido Pasquariello Luciano Guerriero Arcangelo Distante Interferometric SAR Phase Unwrapping by Parallel Tempering on a APE100/Quadrics Supercomputer. 898-900 1998 conf/hpcn/1998 HPCN Europe db/conf/hpcn/hpcn1998.html#StramagliaPGD98 https://doi.org/10.1007/BFb0037226 Alberto Refice Maria Teresa Chiaradia Luciano Guerriero Giovanni Nico Palma N. Blonda Guido Pasquariello Giuseppe Satalino Sebastiano Stramaglia Nicola Veneziani Local and global strategies for InSAR phase unwrapping. 0000 1998 SAR https://doi.org/10.1117/12.331345 conf/sar/1998 db/conf/sar/sar1998.html#ReficeCGNBPSSV98

Giovanni Sebastiani Sebastiano Stramaglia A Bayesian approach for the median filter in image processing. 303-309 1997 62 Signal Process. 3 https://doi.org/10.1016/S0165-1684(97)00131-X db/journals/sigpro/sigpro62.html#SebastianiS97

Javier O. Alvarez-Cienfuegos Nicola Ancona Anne E. Anderson P. Anelli Leonardo Angelini Yuri Antonacci Chiara Barà Iege Bassez Roberto Bellotti Palma BlondaPalma N. Blonda Stefano Boccaletti Paolo Bonifazi Fabio Bovenga A. L. Brewster Alessandro Busacca Alberto Cabrera Borja Camino-Pontes Huafu Chen Maria T. ChiaradiaMaria Teresa Chiaradia Alfonso CinoAlfonso C. Cino Kenzo Clauw Domenico Conte Jesús M. CortésJesús M. Cortés Diaz Barbora Czippelova Jerry Jones David Ibai Díez Jurong Ding Arcangelo Distante U. Emiliani J. M. Encinas Asier Erramuzpe Iñaki Escudero Luca Faes Alessandro Fania Luca Gerardo-Giorda Luciano Guerriero Marta Iovino Niksa Jakovljevic Sarika Jalan Michal Javorka Henrik Jeldtoft JensenHenrik J. Jensen Antonio Jimenez-Marin Karolina K. Kasas-Lazetic Dragan Kljajic Jana Krohova Julia M. Kroos Antonio Lacalamita Lucas Lacasa Ivan Lazic Wei Liao 0001 Joseph T. Lizier Andrea I. Luppi Roberto Maestri Mirjana Maletic-Savatic Rosario N. Mantegna Daniele Marinazzo Endika Martinez-Gutierrez Beatriz Mateos T. Di Matteo Nikoleta Mazgutova Pedro A. M. Mediano Gorana Mijatovic Miodrag Milutinov Ludovico Minati Alfonso Monaco Alessandro Montalto Giovanni Nico Luigi Nitti Giandomenico Nollo Maider Nuñez-Ibero Raffaele Nutricato Davide Nuzzi Marlis Ontivero-Ortega Guido Pasquariello Mario Pellicoro Riccardo Pernice Gian Domenico Pinna Alberto Porta Roberto Prevete Javier Rasero Alberto Refice Leonardo Ricci Fernando RosasFernando E. Rosas Narayan G. Sabhahit Marco Sammartino Ernesto J. Sanz-Arigita Giuseppe Satalino Tomas Scagliarini Giovanni Sebastiani Amanda Sierra Laura Sparacino Armando Sternieri Salvatore Stivala Stephan P. Swinnen Giovanni Tessitore Marina de Tommaso Gabriele Trotta Salvatore A. Tupputi Zuzana Turianikova Thomas F. Varley Nicola Veneziani Guorong Wu 0003Guo-Rong Wu 0003