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Reversion of bacteriophage T4rIImutants by high levels of pyrimidine deoxyribonucleosides

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Summary

High levels of pyrimidine deoxyribonucleosides, but not purine deoxyribonucleosides, increase the reversion rate of bacteriophage T4rII mutants to r +. This increased reversion rate is not observed when a thymidine kinase mutation is introduced into the bacteriophage, but the high reversion rate persists when the host, E. coli, harbors a thymidine kinase mutation.

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Authors and Affiliations

  1. Department of Microbiology, New York Medical College, 10595, Valhalla, NY, USA

    JoAnne K. De Vries & Susan S. Wallace

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  1. JoAnne K. De Vries
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  2. Susan S. Wallace
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Communicated by G. O'Donovan

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De Vries, J.K., Wallace, S.S. Reversion of bacteriophage T4rIImutants by high levels of pyrimidine deoxyribonucleosides. Molec. Gen. Genet. 186, 101–105 (1982). https://doi.org/10.1007/BF00422919

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  • DOI: https://doi.org/10.1007/BF00422919

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