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Эчтәлеккә күчү

THY1

Wikipedia — ирекле энциклопедия проектыннан ([http://tt.wikipedia.org.ttcysuttlart1999.aylandirow.tmf.org.ru/wiki/THY1 latin yazuında])
THY1
Нинди таксонда бар H. sapiens[1]
Кодлаучы ген THY1[d][1]
Молекуляр функция связывание с белками плазмы[d][2][3], enzyme binding[d][4], GPI anchor binding[d][4][4][5], GTPase activator activity[d][4][4][5], protein kinase binding[d][4][5], integrin binding[d][6][7][8][…] һәм integrin binding[d][9][10][4][…]
Күзәнәк компоненты цитозоль[d][4], мембрана[d][4], фокальные контакты[d][11], Конус роста[d][4][4], anchored component of plasma membrane[d][4], күзәнәк мембранасы өлеше[d][12], apical plasma membrane[d][13], эндоплазматик челтәр[4], anchored component of membrane[d][4], экзосома[d][14][15][16], наружная сторона клеточной мембраны[d][4][4], липидный рафт[d][17][4][5], anchored component of external side of plasma membrane[d][4][5], дендрит[d][4][5], миелиновая оболочка[d][8][8], күзәнәк тышындагы өлкә[d][4], күзәнәк мембранасы[d][8][18][8][…], күзәнәк өслеге[d][4][19], axolemma[d][4][4], dendrite membrane[d][4][4], neuronal cell body membrane[d][4][4], күзәнәк мембранасы[d][4][4][4][…], фокальные контакты[d][20], миелиновая оболочка[d][5] һәм экзосома[d][21][22]
Биологик процесс negative regulation of T cell receptor signaling pathway[d][4][4], positive regulation of GTPase activity[d][8][8], protein autophosphorylation[d][4], negative regulation of protein kinase activity[d][4][4][5], агрегация клеток[d][4], negative regulation of cell migration[d][4][4][5], Ангиогенез[d][4][4][5], negative regulation of axonogenesis[d][4][4][5], cytoskeleton organization[d][4][4][5], regulation of cell migration[d][4], positive regulation of T cell activation[d][4][4][5], T cell receptor signaling pathway[d][4][4][5], retinal cone cell development[d][4][4][5], positive regulation of release of sequestered calcium ion into cytosol[d][4][4][5], C-terminal protein lipidation[d][8], regulation of cell-matrix adhesion[d][19], positive regulation of cellular extravasation[d][9], integrin-mediated signaling pathway[d][10][4], передача сигнала между клетками[d][23][4], positive regulation of heterotypic cell-cell adhesion[d][9], receptor clustering[d][4][4], positive regulation of focal adhesion assembly[d][10][4], negative regulation of protein tyrosine kinase activity[d][4][4], negative regulation of neuron projection regeneration[d][23][4], regulation of Rho-dependent protein serine/threonine kinase activity[d][10][4], focal adhesion assembly[d][8][8], cell-cell adhesion[d][4][4], positive regulation of GTPase activity[d][4][4][5] һәм focal adhesion assembly[d][4][4][5]
Изображение Gene Atlas

THY1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[24][25]

Искәрмәләр

[үзгәртү | вики-текстны үзгәртү]
  1. 1 2 UniProt
  2. ↑ Aust G. Thy-1 (CD90) is an interacting partner for CD97 on activated endothelial cells, Thy-1 (CD90) Is an Interacting Partner for CD97 on Activated Endothelial Cells // J. Immunol. — Baltimore: 2012. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.1003944 — PMID:22210915
  3. ↑ M Marsh Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes // J. Cell Biol. / J. Nunnari — Rockefeller University Press, 1994. — ISSN 0021-9525; 1540-8140 — doi:10.1083/JCB.125.3.639 — PMID:7513706
  4. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 GOA
  5. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  6. ↑ Chavakis T., Preissner K. T., Anderegg U. Human Thy-1 (CD90) on activated endothelial cells is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18) // J. Immunol. — Baltimore: 2004. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.172.6.3850 — PMID:15004192
  7. ↑ Schneider P., Andrew F G Quest, Herrera-Molina R. Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication // Biochim. Biophys. Acta — Elsevier, 2008. — ISSN 0006-3002; 1878-2434 — doi:10.1016/J.BBAMCR.2008.01.034 — PMID:18346467
  8. 1 2 3 4 5 6 7 8 9 10 GOA
  9. 1 2 3 Chavakis T., Preissner K. T., Anderegg U. Human Thy-1 (CD90) on activated endothelial cells is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18) // J. Immunol. — Baltimore: 2004. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.172.6.3850 — PMID:15004192
  10. 1 2 3 4 Schneider P., Andrew F G Quest, Herrera-Molina R. Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication // Biochim. Biophys. Acta — Elsevier, 2008. — ISSN 0006-3002; 1878-2434 — doi:10.1016/J.BBAMCR.2008.01.034 — PMID:18346467
  11. ↑ Waterman C., Yates J. R. Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation // Nat. Cell Biol. — NPG, 2011. — ISSN 1465-7392; 1476-4679 — doi:10.1038/NCB2216 — PMID:21423176
  12. ↑ Seki T, HC C., Moriuchi T et al. Thy-1: a hydrophobic transmembrane segment at the carboxyl terminus // Fed Proc — 1985. — ISSN 0014-9446 — PMID:2864289
  13. ↑ Kizhatil K., Bennett V. Lateral membrane biogenesis in human bronchial epithelial cells requires 190-kDa ankyrin-G // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2004. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M314296200 — PMID:14757759
  14. ↑ Farina A., Lane L., Lescuyer P. et al. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine // Journal of Proteomics — Elsevier, 2013. — ISSN 1874-3919; 0165-022X — doi:10.1016/J.JPROT.2013.01.012 — PMID:23376485
  15. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  16. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  17. ↑ Settleman J. Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity // Exp. Cell. Res. — Academic Press, Elsevier, 2004. — ISSN 0014-4827; 1090-2422 — doi:10.1016/J.YEXCR.2004.01.026 — PMID:15093746
  18. ↑ T. Moriuchi, Chang H. C., R. Denome et al. Thy-1 cDNA sequence suggests a novel regulatory mechanism // Nature / M. Skipper — NPG, Springer Science+Business Media, 1983. — ISSN 1476-4687; 0028-0836 — doi:10.1038/301080A0 — PMID:6130472
  19. 1 2 A. Saalbach, R. Kraft, K. Herrmann et al. The monoclonal antibody AS02 recognizes a protein on human fibroblasts being highly homologous to Thy-1 // Archives of Dermatological Research — Springer Science+Business Media, 1998. — ISSN 0340-3696; 1432-069X — doi:10.1007/S004030050318 — PMID:9749990
  20. ↑ Waterman C., Yates J. R. Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation // Nat. Cell Biol. — NPG, 2011. — ISSN 1465-7392; 1476-4679 — doi:10.1038/NCB2216 — PMID:21423176
  21. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  22. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  23. 1 2 Gundelfinger E. D., Schneider P., Andrew F G Quest et al. Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1 // PLOS ONE / PLOS ONE Editors — PLoS, 2012. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0034295 — PMID:22479590
  24. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланган. 18 сентябрь, 2017 тикшерелгән.
  25. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

[үзгәртү | вики-текстны үзгәртү]
  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


Чыганак — https://tt.wikipedia.org/w/index.php?title=THY1&oldid=5520377