UROD

UROD
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1JPH, 1JPI, 1JPK, 1R3Q, 1R3R, 1R3S, 1R3T, 1R3V, 1R3W, 1R3Y, 1URO, 2Q6Z, 2Q71, 3GVQ, 3GVR, 3GVV, 3GVW, 3GW0, 3GW3
Dynodwyr
Cyfenwau	UROD, PCT, UPD, uroporphyrinogen decarboxylase
Dynodwyr allanol	OMIM: 613521 HomoloGene: 320 GeneCards: UROD
EC number	4.1.1.37
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • lyase activity • uroporphyrinogen decarboxylase activity • carboxy-lyase activity Cydrannau o'r gell • nucleoplasm • cytoplasm • cytosol Prosesau biolegol • protoporphyrinogen IX biosynthetic process • porphyrin-containing compound biosynthetic process • heme biosynthetic process • heme metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7389	n/a
Ensembl	ENSG00000126088	n/a
UniProt	P06132	n/a
RefSeq (mRNA)	NM_000374	n/a
RefSeq (protein)	NP_000365	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UROD yw UROD a elwir hefyd yn Uroporphyrinogen decarboxylase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p34.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UROD.

• PCT
• UPD

Llyfryddiaeth

• "Hepatoerythropoietic Porphyria Caused by a Novel Homoallelic Mutation in Uroporphyrinogen Decarboxylase Gene in Egyptian Patients. ". Folia Biol (Praha). 2015. PMID 26789143.
• "Computational identification of pathogenic associated nsSNPs and its structural impact in UROD gene: a molecular dynamics approach. ". Cell Biochem Biophys. 2014. PMID 24777812.
• "Familial porphyria cutanea tarda in Spain: characterization of eight novel mutations in the UROD gene and haplotype analysis of the common p.G281E mutation. ". Gene. 2013. PMID 23545314.
• "Uroporphyrinogen decarboxylase as a potential target for specific components of traditional Chinese medicine: a virtual screening and molecular dynamics study. ". PLoS One. 2012. PMID 23209648.
• "Molecular analysis of the UROD gene in 17 Argentinean patients with familial porphyria cutanea tarda: characterization of four novel mutations.". Mol Genet Metab. 2012. PMID 22382040.