Science

A 1°C rise in temperature is a poverty multiplier. New global evidence based on subnational data from 130 countries shows that each additional degree of warming: ✖️ Increases poverty by 0.63–1.18 percentage points ✖️ Raises inequality by 1.3–1.9% (Gini index) ✖️ Pushes 62–99 million more people into poverty by 2030 compared to a world without climate change The impacts are not evenly distributed. They are strongest in poorer countries, especially where agriculture dominates livelihoods, and are particularly acute across Sub-Saharan Africa. When we look only at national averages, much of the damage disappears. But subnational analysis reveals the real story: large, localized climate shocks interacting with poverty, inequality, and vulnerability. This matters for policy, finance, and development planning. If we underestimate climate risk by relying on national-level data, we: 1️⃣ Misprice climate risk 2️⃣ Misallocate adaptation finance 3️⃣ Miss the communities most exposed Climate change is no longer just about emissions trajectories. It is about distributional impacts, justice, and who pays the price first. This is why granular climate intelligence must sit at the heart of poverty reduction, adaptation, and development strategies. Because climate risk is not abstract. It is local, unequaland already reshaping development outcomes. read the article in Nature here 👇 https://lnkd.in/ehtBmjip

Today, I’m thrilled to share what I believe is the biggest breakthrough in microbiome science for a decade. Nature Magazine, the world's most influential scientific journal, has just published a scientific paper by ZOE's scientists, establishing the first reliable, repeatable, global way to measure the health of an individual’s gut microbiome. It represents the culmination of eight years of work at ZOE. Scientists have been trying to solve this puzzle for more than 20 years, right back to when they first discovered how important our gut microbes are for our health. It’s been achieved only because more than 34,000 ZOE members took part in this research. We’ve known for a long time that the microbiome is linked to cholesterol, inflammation, blood sugar control and even how we store fat. But we’ve never had a clear, evidence-based way to measure how healthy a microbiome actually is. This analysis finally delivers it, revealing a global ranking of microbes that works across populations, diets and environments. The insights are remarkable. Among the top 50 “good microbes” linked with better health, 22 were completely unknown to science until today, and most of the others have never been successfully grown in a lab. We also discovered clear links between these good microbes and health outcomes: healthy individuals carry around 3.6 more of these beneficial species, and people at a healthy weight carry about 5.2 more than those living with obesity. We also found a strong connection to diet. People eating healthier diets consistently have microbiomes that score better on this ranking. What we eat shapes our gut health, and now we can measure this relationship with unprecedented clarity. ZOE was created to enable microbiome research at a scale that traditional science has been unable to fund, and use this research to create actionable advice that can transform our gut health. This is a major milestone in that journey. I’m delighted to say that as a result, this breakthrough science is immediately available for the public to investigate their own microbiome through ZOE’s new Gut Health Test in the UK, and this is coming soon in the US. You can now receive not only a reliable measurement of how healthy your microbiome is as you change their diet, but also discover the health of clusters of gut microbes in your gut affecting metabolism, inflammation and more. To all our amazing ZOE members who have participated in our science: you made this possible. You are transforming our understanding of the microbiome. Thank you so much. I hope you feel as proud and excited as I do. I should note that your research is now published in Nature, which is the ultimate scientific accolade, and you can definitely brag about that with your friends! If you think this science could help others understand their health, I’d love for you to share it. You’ll find links to more details from our findings and access to the paper in the comments.

Agrivoltaics – combining land for solar and agriculture – is a genuine win-win. It allows a single piece of land to produce both food and clean energy at the same time. Around the world, farmers are finding that solar infrastructure creates microhabitats that boost resilience, improve yields and reduce water stress. For the agriculture: ✅ Shade from the panels lower ground temperatures and reduces evaporation. In arid areas, this has doubled or even tripled crop yields while cutting irrigation needs by half. ✅ Shade-tolerant crops like lettuce, kale, berries and broccoli thrive under reduced heat stress, especially during extreme weather. ✅ Higher soil moisture also promotes healthier pasture, leading to more nutritious forage for grazing animals. For solar operators: ✅ Sheep naturally keep vegetation under control, reducing mowing and maintenance costs and lowering fire risk. They also prevent plants from shading the panels. ✅ Crops underneath the panels help to cool the modules, improving performance on hot days. And the animals benefit too. A 3-year study of 1,700 sheep at the Wellington Solar Farm in NSW found the sheep produced higher quality wool and more of it. The arrays offer shade in summer, shelter during storms and cooler microclimates throughout the day. Economically it's a strong proposition: - Landowners gain a stable income stream while keeping land productive. - Developers access more viable sites with fewer permitting hurdles. - Communities retain agricultural land and benefit from local investment and tax revenue. And in the US, a significant "solar grazing" industry is emerging, where farmers become vegetation managers. They rent out flocks of sheep to solar farm owners and the sheep trim the vegetation. Agrivoltaics is showing that solar and agriculture don’t have to compete for land. They can thrive together – and create more value in the process. Image credit: Enel Green Power #energy #renewables #energytransition

MIT just cleared 50% of Alzheimer's plaques using 40 Hz sound waves. No drugs. No surgery. Just precisely engineered frequencies making immune cells devour toxic proteins. Frequency is becoming medicine's most powerful tool. Think about that. While we've spent decades failing with Alzheimer's drugs, MIT researchers discovered something extraordinary: exposing brains to 40 Hz gamma frequencies activates microglia—the brain's cleanup crew—to clear amyloid plaques naturally. Mice regained memory. Human trials are showing promise. This isn't alternative medicine. It's FDA-approved precision. Traditional Brain Treatment: ↳ Invasive surgery with months of recovery ↳ Drugs that barely slow decline ↳ Blood-brain barrier blocking 98% of medications ↳ Essential tremor requiring skull opening The Frequency Revolution: ↳ 60% tremor reduction in one ultrasound session ↳ Same-day discharge, no incisions ↳ Drug delivery increased 5-fold to brain tumors ↳ 90+ clinical trials transforming neurology But here's what stopped me cold: Focused ultrasound doesn't destroy tissue—it tunes it. Opening the blood-brain barrier for exactly 4 hours to deliver chemotherapy. Synchronizing neurons at 40 Hz to trigger natural healing. Making Parkinson's tremors vanish while patients stay awake, go home that afternoon. We're not attacking disease anymore. We're conducting it away. What changes everything: ↳ Brain surgery without cutting ↳ Alzheimer's clearing without drugs ↳ Tumors targeted without systemic poison ↳ Healing through harmony, not harm The Multiplication Effect: 1 frequency device = surgery avoided 10 hospitals equipped = tremor wards emptying 100 conditions targeted = non-invasive becomes standard At scale = medicine's violent era ends Stanford uses ultrasound for depression. Johns Hopkins for addiction. Mayo Clinic for brain tumors. Each discovering that precisely tuned frequencies can reprogram biology better than any drug. We spent centuries cutting and poisoning disease. Now we're tuning it out of existence. Because when 40 Hz can clear plaques that billion-dollar drugs couldn't touch, and ultrasound can perform brain surgery without a scalpel, we're not just advancing medicine. We're using medical precision. Follow me, Dr. Martha Boeckenfeld for breakthroughs where physics becomes pharmacy. ♻️ Share if you want other to learn about new possibilities to fight Alzheimer. Resources: Gamma frequency entrainment attenuates amyloid load and modifies microglia" Authors: Li-Huei Tsai et al. NatureDecember 2016 DOI: 10.1038/nature20587. Gamma frequency sensory stimulation in mild probable Alzheimer’s dementia: Phase 2A pilot study" PLOS Biology, November 30, 2022 Evidence that 40Hz gamma stimulation promotes brain health,” Li-Huei Tsai, PLOS Biology, 2025.

The impact of climate change on the SDGs 🌎 The latest State of the Global Climate 2024 report from WMO provides a clear assessment of how accelerating climate change is affecting global stability. With 2024 recorded as the hottest year on record—1.55°C above pre-industrial levels—the implications extend far beyond temperature increases. The findings highlight the direct and systemic risks climate change poses to achieving the UN Sustainable Development Goals (SDGs). Rising temperatures, ocean acidification, sea-level rise, and glacial melt are driving widespread environmental and socio-economic disruptions. These changes are not occurring in isolation; they are interconnected, amplifying existing challenges related to food security (SDG 2), water availability (SDG 6), economic resilience (SDG 8), and biodiversity loss (SDGs 14 & 15). Ocean changes are among the most critical risks. Increasing ocean temperatures and acidification are disrupting marine ecosystems, reducing fish stocks, and weakening the ocean’s ability to act as a carbon sink. This has significant consequences for coastal communities, food security, and global supply chains. Glacial loss and sea-level rise are reshaping landscapes, affecting infrastructure, water resources, and human settlements. Coastal erosion, land degradation, and increased flooding threaten urban development (SDG 11), economic productivity (SDG 9), and disaster resilience (SDG 13). These impacts also contribute to population displacement, further straining social and economic systems. The increase in extreme weather events, from heatwaves to hurricanes, is exacerbating global inequality. Agricultural losses, infrastructure damage, and rising adaptation costs are disproportionately affecting developing regions, slowing progress toward economic stability, sustainable production, and resource security (SDGs 8 & 12). The WMO report emphasizes that while exceeding 1.5°C in a single year does not mean the Paris Agreement target has been breached, the trend underscores the urgency of reducing emissions and strengthening adaptation strategies. Without immediate action, climate risks will continue to escalate, undermining progress toward the SDGs and increasing long-term economic and environmental costs. Addressing these challenges requires systemic policy shifts, investment in climate resilience, and cross-sector collaboration. As climate change intensifies, integrating sustainability into decision-making at all levels will be essential to mitigating risks and safeguarding global development objectives. Source: State of the Global Climate 2024 #sustainability #sustainable #business #esg #climatechange #sdgs

What happens when companies break their climate promises? Almost nothing. A new study has uncovered troubling truths about corporate climate commitments. Out of 1,041 companies with emissions reduction targets set for 2020: -9% (88 firms) openly failed to meet their goals. -31% (320 firms) stopped reporting on their targets without explanation. What happens when companies miss these targets? Practically no consequences: -Only three failed companies faced media scrutiny. -No significant market backlash, media sentiment shifts, or ESG rating downgrades. In contrast, companies were rewarded with positive press and improved ESG ratings simply for announcing these targets. The bigger issue: This accountability gap threatens the credibility of ambitious 2030 and 2050 climate pledges. Unlike financial targets, which are rigorously monitored, emissions goals often exist in a vacuum—without oversight or real consequences for failure. Interestingly, the study found that: -Firms in common-law countries and those with stronger media accountability had better success rates. -High-emitting sectors like energy and materials struggled the most, with the highest rates of "disappeared" targets. With more companies backing away from climate action, we cannot afford to let this cycle continue. It’s time for corporate sustainability leadership to move beyond announcements and deliver measurable, transparent results. Accountability mechanisms—demanded by both regulators and stakeholders are urgently needed. A great piece of work by Xiaoyan Jiang, Shawn Kim, and Shirley Simiao Lu! Let’s learn from these insights to ensure that corporate climate pledges actually deliver. #climatechange #netzero #esg

Had to share the one prompt that has transformed how I approach AI research. 📌 Save this post. Don’t just ask for point-in-time data like a junior PM. Instead, build in more temporal context through systematic data collection over time. Use this prompt to become a superforecaster with the help of AI. Great for product ideation, competitive research, finance, investing, etc. ⏰⏰⏰⏰⏰⏰⏰⏰⏰⏰⏰⏰ TIME MACHINE PROMPT: Execute longitudinal analysis on [TOPIC]. First, establish baseline parameters: define the standard refresh interval for this domain based on market dynamics (enterprise adoption cycles, regulatory changes, technology maturity curves). For example, AI refresh cycle may be two weeks, clothing may be 3 months, construction may be 2 years. Calculate n=3 data points spanning 2 full cycles. For each time period, collect: (1) quantitative metrics (adoption rates, market share, pricing models), (2) qualitative factors (user sentiment, competitive positioning, external catalysts), (3) ecosystem dependencies (infrastructure requirements, complementary products, capital climate, regulatory environment). Structure output as: Current State Analysis → T-1 Comparative Analysis → T-2 Historical Baseline → Delta Analysis with statistical significance → Trajectory Modeling with confidence intervals across each prediction. Include data sources. ⏰⏰⏰⏰⏰⏰⏰⏰⏰⏰⏰⏰

My colleague Prof. Eleanor Maguire passed away this weekend after a long battle with cancer. Her contributions to #neuroscience have shaped how we understand memory and navigation, leaving a lasting legacy. One of Eleanor’s groundbreaking discoveries was that when a London taxi driver learns the 25,000 windy streets of London together with thousands of landmarks (collectively called “the Knowledge”), it physically changes their #brain. A part of the brain called the #hippocampus is important both for making new memories and for navigating one’s environment. For aspiring black cab drivers, learning the Knowledge pushes the hippocampus to adapt in remarkable ways. Eleanor and her colleagues used #MRI to measure the hippocampus in taxi drivers compared to a control group and discovered it was larger in the taxi drivers. In other words, London cabbies have special brains that are particularly well suited for their work. This raises a really interesting question: Are they born with a larger hippocampus and therefore better able to become taxi drivers or does learning the Knowledge change their brains? To answer this, Eleanor and her team ran a follow-up study where they followed 39 trainee taxi drivers from the beginning of their training to when qualified approximately 4 years later. Each received a brain scan at the beginning and end of their training. 👉 Before training, the aspiring taxi drivers showed no difference in hippocampus size compared to matched control volunteers. 👉 After training, the newly qualified taxi drivers were found to have larger hippocampi than they did 4 years ago and also larger than the control volunteers. In other words, even as an adult, learning the Knowledge has a strong effect on the brain that can be measured using MRI. Eleanor’s work has become one of the most well-known examples of #neuroplasticity, which is the brain’s remarkable ability to change and adapt throughout life. A few years ago, a group of students were visiting UCL’s Functional Imaging Lab. They had learned about her taxi study in their A-level psychology class so when they discovered that Eleanor worked there, there was a frenzy of excitement! They couldn’t believe that they got to meet the “Maguire” whose work they had read in school. It was absolutely charming! Although best known for work with taxi drivers, Eleanor made substantial contributions to memory and hippocampal function including: 👉 Discovering that patients with amnesia cannot imagine the future 👉 Showing that it is possible to decode individual memories by analysing patterns of activity in the hippocampus 👉 Clarifying the relation between memory for life episodes, the ability to imagine the future, and the ability to navigate spatial environments Eleanor’s work is a powerful reminder of the brain’s potential to adapt and grow throughout life. May her legacy inspire all of us to keep learning and exploring the frontiers of science.

If your paper is getting rejected, it isn’t necessarily the science that’s the problem (it’s likely the journal fit that’s off!). Here’s how you can be be strategic about journal selection. How do I choose the right scientific journal? ↳ Analyze your citation list and target relevant publications. Can impact factor really determine journal quality? ↳ Look beyond numbers, focus on specialized audience fit. How to avoid predatory journal publication traps? ↳ Verify journal reputation before submitting your research. Will editors help improve my manuscript? ↳ Follow author guidelines meticulously. Navigating the academic publication landscape can feel like traversing a complex maze. As a professor, I've learned that selecting the right journal is both an art and a science. Here's a game-changing approach I've developed: 1. Conduct a citation audit: Count journals you've referenced most frequently. These are likely your ideal publication targets. 2. Beyond Impact Factor: Don't get fixated on numbers. A lower-ranked journal with a specialized audience might be more valuable than a high-impact generic publication. 3. Beware of predatory journals: If an unsolicited email promises quick publication for a fee, run! Legitimate open-access journals conduct rigorous peer review. 4. Craft a strategic cover letter: Suggest credible reviewers, highlight your paper's novelty, and demonstrate professionalism. 5. Patience is key: Most journals reject approximately 50% of submissions. Don't be discouraged - each submission is a learning opportunity. Pro tip: Always read and follow the journal's specific author guidelines. This shows you're a detail-oriented, professional researcher. Have you ever struggled with selecting the right scientific journal for your research? What challenges have you encountered? #science #scientist #ScientificCommunication #publishing #phd #professor #research #postgraduate

🔥 Climate risks are no longer abstract—they’re disrupting businesses, communities, and economies right now. The World Economic Forum’s 2024 report, "The Cost of Inaction: A CEO Guide to Navigating Climate Risk", delivers a sobering message: ignoring climate risks isn’t just irresponsible—it’s economically devastating. 🌡️ Key insights from the report: 💥 Climate-related disasters have caused $3.6 trillion in damages since 2000, exposing critical vulnerabilities in supply chains and infrastructure. 📉 Physical risks could put 5-25% of EBITDA at risk for some sectors by 2050 under a 3°C warming trajectory. 💸 Transition risks, like carbon pricing and changing regulations, could impact 50% of EBITDA in energy-intensive industries by 2030. 🌱 Every $1 invested in climate adaptation yields $2-$19 in avoided costs, while green markets are projected to grow from $5 trillion in 2024 to $14 trillion by 2030. 💡 My reflections: 🔄 Resilience isn’t enough anymore. Too often, we focus on simply "weathering the storm" of climate risk. But true leadership is about rebuilding something better—rethinking markets, redesigning business models, and creating solutions that lead entire industries forward. 🌍 Supply chain fragility is the Achilles’ heel of the global economy. A single extreme weather event can cascade across operations, grinding everything to a halt. Climate-resilient supply chains can’t just be about survival—they must be radically adaptive, decentralized, and built to thrive under disruption. 📊 Climate risk is fundamentally redefining the concept of value. Businesses stuck chasing quarterly earnings are missing the bigger picture. In a world of rising costs and irreversible climate impacts, long-term value will belong to those who embed sustainability, resilience, and equity into their strategies. The time for cautious, incremental steps has passed. How are we using this moment to transform the way we work, innovate, and lead? #ClimateAction #Sustainability #Resilience #Leadership #Innovation