SLC11A2

SLC11A2
Identifiants
Alias	SLC11A2
IDs externes	OMIM: 600523 MGI: 1345279 HomoloGene: 55471 GeneCards: SLC11A2
Position du gène (humain) Chr. Chromosome 12 humain Locus 12q13.12 Début 50,979,401 bp Fin 51,028,566 bp
Position du gène (souris) Chr. Chromosome 15 (souris) Locus 15 F1|15 56.29 cM Début 100,285,779 bp Fin 100,322,953 bp
Expression génique Bgee Humain Souris (orthologue) Fortement exprimé dans ganglion inférieur du nerf vague buccal mucosa cell caput epididymis corps calleux cartilage tissue cavité buccale glande salivaire accessoire noyau vestibulaire supérieur noyau sous-thalamique pont Fortement exprimé dans epithelium of small intestine Ileal epithelium spermatocyte duodénum lèvre right kidney primary oocyte fetal liver hematopoietic progenitor cell proximal tubule Vésicule vitelline Plus de données d'expression de référence BioGPS Plus de données d'expression de référence
Gene Ontology Fonction moléculaire vanadium ion transmembrane transporter activity transporter activity transition metal ion transmembrane transporter activity lead ion transmembrane transporter activity proton transmembrane transporter activity cadmium ion binding manganese ion transmembrane transporter activity cobalt ion transmembrane transporter activity zinc ion transmembrane transporter activity chromium ion transmembrane transporter activity solute:proton symporter activity liaison protéique copper ion transmembrane transporter activity nickel cation transmembrane transporter activity calcium ion transmembrane transporter activity inorganic cation transmembrane transporter activity cadmium ion transmembrane transporter activity iron ion transmembrane transporter activity ferrous iron transmembrane transporter activity iron ion binding copper ion binding zinc ion binding nickel cation binding manganese ion binding metal ion transmembrane transporter activity cobalt ion binding Composant cellulaire cytoplasme endosome membrane basal part of cell Rétromère trans-Golgi network perinuclear region of cytoplasm noyau late endosome membrane surface cellulaire membrane mitochondrial externe apical plasma membrane lysosome integral component of membrane recycling endosome late endosome membrane plasmique partie apicale d'une cellule early endosome bordure en brosse endosome membrane paraferritin complex integral component of plasma membrane brush border membrane lysosomal membrane vacuole vésicule cytoplasmique système endomembranaire mitochondrie vésicule extracellulaire Processus biologique cadmium ion transmembrane transport activation of cysteine-type endopeptidase activity involved in apoptotic process proton transmembrane transport lead ion transport iron ion homeostasis ion transport heme biosynthetic process multicellular organismal iron ion homeostasis apprentissage ou mémoire iron ion transmembrane transport dendrite morphogenesis porphyrin-containing compound biosynthetic process response to iron ion iron ion transport copper ion transport response to hypoxia cobalt ion transport detection of oxygen cellular response to oxidative stress manganese ion transport nickel cation transport erythrocyte development porphyrin-containing compound metabolic process cellular iron ion homeostasis cation transmembrane transport manganese ion transmembrane transport vanadium ion transport zinc ion transmembrane transport nickel cation transmembrane transport copper ion transmembrane transport transport metal ion transport iron import into cell Sources:Amigo / QuickGO
Orthologues Espèces Homme Souris Entrez 4891 18174 Ensembl ENSG00000110911 ENSMUSG00000023030 UniProt P49281 P49282 RefSeq (mRNA) NM_000617 NM_001174125 NM_001174126 NM_001174127 NM_001174128 NM_001174129 NM_001174130 NM_001379446 NM_001379447 NM_001379448 NM_001379455 NM_001146161 NM_008732 NM_001356952 RefSeq (protéine) NP_000608 NP_001167596 NP_001167597 NP_001167598 NP_001167599 NP_001167600 NP_001167601 NP_001366375 NP_001366376 NP_001366377 NP_001366384 NP_001139633 NP_032758 NP_001343881 Localisation (UCSC) Chr 12: 50.98 – 51.03 Mb Chr 15: 100.29 – 100.32 Mb Publication PubMed
Wikidata
Voir/Editer Humain Voir/Editer Souris

SLC11A2 est un gène situé sur le chromosome 12 humain.

Maladies liées

• Anémie microcytaire avec surcharge hépatique en fer