SLC8A1

SLC8A1
Identifiants
Alias	SLC8A1
IDs externes	OMIM: 182305 MGI: 107956 HomoloGene: 69090 GeneCards: SLC8A1
Position du gène (humain) Chr. Chromosome 2 humain Locus 2p22.1 Début 40,097,270 bp Fin 40,611,053 bp
Position du gène (souris) Chr. Chromosome 17 (souris) Locus 17 E3|17 51.29 cM Début 81,680,534 bp Fin 82,045,806 bp
Expression génique Bgee Humain Souris (orthologue) Fortement exprimé dans ventricule droit cellule endothéliale Veine saphène Brodmann area 23 epithelium of colon veine cave myocarde gyrus postcentral cardiac muscle tissue of right atrium gyrus temporal moyen Fortement exprimé dans lateral septal nucleus cardiac muscle tissue of left ventricle lumbar subsegment of spinal cord ventromedial nucleus corps géniculé latéral lateral hypothalamus substantia nigra pontine nuclei medullary collecting duct corps mamillaires Plus de données d'expression de référence BioGPS n/a
Gene Ontology Fonction moléculaire ankyrin binding calcium liaison ionique liaison ion métal antiporter activity fixation de la calmoduline transmembrane transporter binding cytoskeletal protein binding liaison protéique calcium:sodium antiporter activity ion antiporter activity involved in regulation of postsynaptic membrane potential calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration Composant cellulaire sarcolemma integral component of membrane mitochondrie prolongement cellulaire dendritic shaft integral component of plasma membrane épine dendritique membrane microtubule Z discdkac intercalated disc T-tubule nucléoplasme membrane plasmique membrane postsynaptique integral component of postsynaptic membrane Processus biologique response to muscle stretch contraction musculaire response to hypoxia cellular response to caffeine telencephalon development positive regulation of fibroblast migration cellular response to cAMP regulation of cardiac conduction response to ATP regulation of sodium ion transport regulation of heart rate vascular associated smooth muscle contraction response to immobilization stress cellular sodium ion homeostasis positive regulation of the force of heart contraction positive regulation of bone mineralization positive regulation of cytosolic calcium ion concentration relaxation of smooth muscle cellular calcium ion homeostasis calcium ion homeostasis calcium ion transport into cytosol communication cellulaire cell communication by electrical coupling involved in cardiac conduction ion transport regulation of calcium ion transport regulation of cell communication by electrical coupling regulation of cardiac muscle contraction by calcium ion signaling cardiac muscle cell development membrane depolarization during cardiac muscle cell action potential cellular response to hypoxia response to glucose response to nutrient response to hydrogen peroxide calcium ion import sodium ion transport calcium ion transport negative regulation of cytosolic calcium ion concentration cardiac muscle contraction sodium ion transmembrane transport regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion regulation of the force of heart contraction calcium ion transmembrane transport relaxation of cardiac muscle transport transmembranaire cellular response to reactive oxygen species calcium ion export Potentiel postsynaptique sodium ion export across plasma membrane sodium ion import across plasma membrane regulation of postsynaptic cytosolic calcium ion concentration Sources:Amigo / QuickGO
Orthologues Espèces Homme Souris Entrez 6546 20541 Ensembl ENSG00000183023 ENSMUSG00000054640 UniProt P32418 P70414 RefSeq (mRNA) NM_001112800 NM_001112801 NM_001112802 NM_001252624 NM_021097 NM_001351483 NM_001351484 NM_001351485 NM_001351486 NM_001351487 NM_001351488 NM_001351489 NM_001351490 NM_001351491 NM_001351492 NM_001351493 NM_001351494 NM_001372263 NM_001394103 NM_001394104 NM_001394105 NM_001394106 NM_001394107 NM_001112798 NM_001286684 NM_011406 RefSeq (protéine) NP_001106271 NP_001106272 NP_001106273 NP_001239553 NP_066920 NP_001338412 NP_001338413 NP_001338414 NP_001338415 NP_001338416 NP_001338417 NP_001338418 NP_001338419 NP_001338420 NP_001338421 NP_001338422 NP_001338423 NP_001359192 NP_001106269 NP_001273613 NP_035536 Localisation (UCSC) Chr 2: 40.1 – 40.61 Mb Chr 17: 81.68 – 82.05 Mb Publication PubMed
Wikidata
Voir/Editer Humain Voir/Editer Souris

SLC8A1 est un gène situé sur le chromosome 2 humain.

Maladies liées

• Maladie cardiovasculaire